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The nocebo effect of informed consent.
Bioethics 2014; 28(3):147-54B

Abstract

The nocebo effect, the mirror-phenomenon to the placebo effect, is when the expectation of a negative outcome precipitates the corresponding symptom or leads to its exacerbation. One of the basic ethical duties in health care is to obtain informed consent from patients before treatment; however, the disclosure of information regarding potential complications or side effects that this involves may precipitate a nocebo effect. While dilemmas between the principles of respect for patient autonomy and of nonmaleficence are recognized in medical ethics, there has not yet been an ethical discussion focused on the potential dilemma raised by the nocebo effect of informed consent (NEIC). This dilemma is especially pernicious, since it involves a direct causality of harm by the caregiver that is unparalleled by other potential harmful effects of information disclosure. This paper articulates the dilemma of the NEIC and offers a seminal ethical analysis.

Authors+Show Affiliations

Ben-Gurion University of the Negev.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22762392

Citation

Cohen, Shlomo. "The Nocebo Effect of Informed Consent." Bioethics, vol. 28, no. 3, 2014, pp. 147-54.
Cohen S. The nocebo effect of informed consent. Bioethics. 2014;28(3):147-54.
Cohen, S. (2014). The nocebo effect of informed consent. Bioethics, 28(3), pp. 147-54. doi:10.1111/j.1467-8519.2012.01983.x.
Cohen S. The Nocebo Effect of Informed Consent. Bioethics. 2014;28(3):147-54. PubMed PMID: 22762392.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The nocebo effect of informed consent. A1 - Cohen,Shlomo, Y1 - 2012/07/05/ PY - 2012/7/6/entrez PY - 2012/7/6/pubmed PY - 2014/12/15/medline KW - autonomy KW - information disclosure KW - informed consent KW - nocebo KW - respect KW - risk-benefit analysis SP - 147 EP - 54 JF - Bioethics JO - Bioethics VL - 28 IS - 3 N2 - The nocebo effect, the mirror-phenomenon to the placebo effect, is when the expectation of a negative outcome precipitates the corresponding symptom or leads to its exacerbation. One of the basic ethical duties in health care is to obtain informed consent from patients before treatment; however, the disclosure of information regarding potential complications or side effects that this involves may precipitate a nocebo effect. While dilemmas between the principles of respect for patient autonomy and of nonmaleficence are recognized in medical ethics, there has not yet been an ethical discussion focused on the potential dilemma raised by the nocebo effect of informed consent (NEIC). This dilemma is especially pernicious, since it involves a direct causality of harm by the caregiver that is unparalleled by other potential harmful effects of information disclosure. This paper articulates the dilemma of the NEIC and offers a seminal ethical analysis. SN - 1467-8519 UR - https://www.unboundmedicine.com/medline/citation/22762392/The_nocebo_effect_of_informed_consent_ L2 - https://doi.org/10.1111/j.1467-8519.2012.01983.x DB - PRIME DP - Unbound Medicine ER -