Tags

Type your tag names separated by a space and hit enter

Royal jelly and bee pollen decrease bone loss due to osteoporosis in an oophorectomized rat model.
Eklem Hastalik Cerrahisi. 2012; 23(2):100-5.EH

Abstract

OBJECTIVES

In this study, we aimed to investigate whether royal jelly and bee pollen reduce the bone loss due to osteoporosis in oophorectomized rat model.

MATERIALS AND METHODS

Thirty-two female Sprague-Dawley mature rats at six-month-old, weighing 180-260 g were used in the study. The rats were divided into four groups: Sham-operation group, only oophorectomy group, oophorectomy in combination with royal jelly group, and oophorectomy and bee pollen group. The rats were sacrified within 12 weeks following surgery. Bone mineral density (BMD) was measured and blood samples were collected for biochemical analysis before sacrification. Following sacrification, uterine weights were measured and tissue samples were taken to determine bone calcium and phosphate level with imaging through scanning electron microscope.

RESULTS

The uterine weights of the rats were found higher in Sham-operation group than the other groups. The difference among the groups was statistically significant (p=0.001). Total body BMD results were similar in all groups and there was not statistically significant difference (p=0.19). The lumbar spine and proximal femur BMD results were statistically significantly higher in the royal jelly and bee pollen groups, compared to only oophorectomy group (p=0.001). Bone tissue calcium and phosphate levels were higher in royal jelly and bee pollen groups.

CONCLUSION

Royal jelly and bee pollen decrease the bone loss due to osteoporosis in oophorectomized rat model. These results may contribute to the clinical practice.

Links

FREE Publisher Full Text

Authors+Show Affiliations

Kafadar IH
Department of Orthopedics and Traumatology, Medical Faculty of Erciyes University, Kayseri, Turkey. ihkafadar@gmail.com
Güney A
No affiliation info available
Türk CY
No affiliation info available
Oner M
No affiliation info available
Silici S
No affiliation info available

MeSH

AnimalsBeesBone DensityDisease Models, AnimalFatty AcidsFemaleHumansOsteoporosis, PostmenopausalOvariectomyPollenRatsRats, Sprague-Dawley

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22765489

Citation

Kafadar, Ibrahim Halil, et al. "Royal Jelly and Bee Pollen Decrease Bone Loss Due to Osteoporosis in an Oophorectomized Rat Model." Eklem Hastaliklari Ve Cerrahisi = Joint Diseases & Related Surgery, vol. 23, no. 2, 2012, pp. 100-5.
Kafadar IH, Güney A, Türk CY, et al. Royal jelly and bee pollen decrease bone loss due to osteoporosis in an oophorectomized rat model. Eklem Hastalik Cerrahisi. 2012;23(2):100-5.
Kafadar, I. H., Güney, A., Türk, C. Y., Oner, M., & Silici, S. (2012). Royal jelly and bee pollen decrease bone loss due to osteoporosis in an oophorectomized rat model. Eklem Hastaliklari Ve Cerrahisi = Joint Diseases & Related Surgery, 23(2), 100-5.
Kafadar IH, et al. Royal Jelly and Bee Pollen Decrease Bone Loss Due to Osteoporosis in an Oophorectomized Rat Model. Eklem Hastalik Cerrahisi. 2012;23(2):100-5. PubMed PMID: 22765489.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Royal jelly and bee pollen decrease bone loss due to osteoporosis in an oophorectomized rat model. AU - Kafadar,Ibrahim Halil, AU - Güney,Ahmet, AU - Türk,Cemil Yildirim, AU - Oner,Mithat, AU - Silici,Sibel, PY - 2012/7/7/entrez PY - 2012/7/7/pubmed PY - 2015/8/19/medline SP - 100 EP - 5 JF - Eklem hastaliklari ve cerrahisi = Joint diseases & related surgery JO - Eklem Hastalik Cerrahisi VL - 23 IS - 2 N2 - OBJECTIVES: In this study, we aimed to investigate whether royal jelly and bee pollen reduce the bone loss due to osteoporosis in oophorectomized rat model. MATERIALS AND METHODS: Thirty-two female Sprague-Dawley mature rats at six-month-old, weighing 180-260 g were used in the study. The rats were divided into four groups: Sham-operation group, only oophorectomy group, oophorectomy in combination with royal jelly group, and oophorectomy and bee pollen group. The rats were sacrified within 12 weeks following surgery. Bone mineral density (BMD) was measured and blood samples were collected for biochemical analysis before sacrification. Following sacrification, uterine weights were measured and tissue samples were taken to determine bone calcium and phosphate level with imaging through scanning electron microscope. RESULTS: The uterine weights of the rats were found higher in Sham-operation group than the other groups. The difference among the groups was statistically significant (p=0.001). Total body BMD results were similar in all groups and there was not statistically significant difference (p=0.19). The lumbar spine and proximal femur BMD results were statistically significantly higher in the royal jelly and bee pollen groups, compared to only oophorectomy group (p=0.001). Bone tissue calcium and phosphate levels were higher in royal jelly and bee pollen groups. CONCLUSION: Royal jelly and bee pollen decrease the bone loss due to osteoporosis in oophorectomized rat model. These results may contribute to the clinical practice. SN - 1309-0313 UR - https://www.unboundmedicine.com/medline/citation/22765489/full_citation/Royal_jelly_and_bee_pollen_decrease_bone_loss_due_to_osteoporosis_in_an_oophorectomized_rat_model_ L2 - http://www.tevak.org/pdf/dergi/2012/pdfsno2/23_2_100_105.pdf DB - PRIME DP - Unbound Medicine ER -