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Determination of haloperidol and hydroxy haloperidol in human plasma by high performance liquid chromatography.
Ann Biol Clin (Paris). 1990; 48(7):455-8.AB

Abstract

A method has been developed for the separation and measurement of haloperidol and hydroxy haloperidol in human plasma through high performance liquid chromatography. The method uses chlorohaloperidol as an internal standard and provides a limit of detection of about 0.7 nmol/l for haloperidol and 0.67 nmol/l for hydroxy haloperidol. HPLC and RIA radioimmunoassay methods are compared.

Authors+Show Affiliations

Laboratoire de Toxicologie, Faculté de Pharmacie, Laguesse, Lille.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

2278409

Citation

Pommery, J, et al. "Determination of Haloperidol and Hydroxy Haloperidol in Human Plasma By High Performance Liquid Chromatography." Annales De Biologie Clinique, vol. 48, no. 7, 1990, pp. 455-8.
Pommery J, Foulon O, Morineau G, et al. Determination of haloperidol and hydroxy haloperidol in human plasma by high performance liquid chromatography. Ann Biol Clin (Paris). 1990;48(7):455-8.
Pommery, J., Foulon, O., Morineau, G., Lhermitte, M., Levron, J. C., & Erb, F. (1990). Determination of haloperidol and hydroxy haloperidol in human plasma by high performance liquid chromatography. Annales De Biologie Clinique, 48(7), 455-8.
Pommery J, et al. Determination of Haloperidol and Hydroxy Haloperidol in Human Plasma By High Performance Liquid Chromatography. Ann Biol Clin (Paris). 1990;48(7):455-8. PubMed PMID: 2278409.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Determination of haloperidol and hydroxy haloperidol in human plasma by high performance liquid chromatography. AU - Pommery,J, AU - Foulon,O, AU - Morineau,G, AU - Lhermitte,M, AU - Levron,J C, AU - Erb,F, PY - 1990/1/1/pubmed PY - 1990/1/1/medline PY - 1990/1/1/entrez SP - 455 EP - 8 JF - Annales de biologie clinique JO - Ann Biol Clin (Paris) VL - 48 IS - 7 N2 - A method has been developed for the separation and measurement of haloperidol and hydroxy haloperidol in human plasma through high performance liquid chromatography. The method uses chlorohaloperidol as an internal standard and provides a limit of detection of about 0.7 nmol/l for haloperidol and 0.67 nmol/l for hydroxy haloperidol. HPLC and RIA radioimmunoassay methods are compared. SN - 0003-3898 UR - https://www.unboundmedicine.com/medline/citation/2278409/Determination_of_haloperidol_and_hydroxy_haloperidol_in_human_plasma_by_high_performance_liquid_chromatography_ DB - PRIME DP - Unbound Medicine ER -