The spectrum of vitamin B12 deficiency.Am Fam Physician. 1990 Jan; 41(1):150-62.AF
Abstract
Low serum vitamin B12 levels are not uncommon in the elderly. Patients with vitamin B12 deficiency manifest a spectrum of clinical findings. Pernicious anemia and malabsorption syndrome are the usual causes of vitamin B12 deficiency. Pernicious anemia is confirmed by the presence of intrinsic factor blocking antibody or abnormal results on the Schilling test. Patients with neuropsychiatric symptoms of vitamin B12 deficiency may have a normal Schilling test and no evidence of macrocytic anemia. In such patients, vitamin B12 deficiency is confirmed by determining serum levels of homocysteine and methylmalonic acid.
Pub Type(s)
Journal Article
Review
Language
eng
PubMed ID
2278533
Citation
Clementz, G L., and S G. Schade. "The Spectrum of Vitamin B12 Deficiency." American Family Physician, vol. 41, no. 1, 1990, pp. 150-62.
Clementz GL, Schade SG. The spectrum of vitamin B12 deficiency. Am Fam Physician. 1990;41(1):150-62.
Clementz, G. L., & Schade, S. G. (1990). The spectrum of vitamin B12 deficiency. American Family Physician, 41(1), 150-62.
Clementz GL, Schade SG. The Spectrum of Vitamin B12 Deficiency. Am Fam Physician. 1990;41(1):150-62. PubMed PMID: 2278533.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - The spectrum of vitamin B12 deficiency.
AU - Clementz,G L,
AU - Schade,S G,
PY - 1990/1/1/pubmed
PY - 1990/1/1/medline
PY - 1990/1/1/entrez
SP - 150
EP - 62
JF - American family physician
JO - Am Fam Physician
VL - 41
IS - 1
N2 - Low serum vitamin B12 levels are not uncommon in the elderly. Patients with vitamin B12 deficiency manifest a spectrum of clinical findings. Pernicious anemia and malabsorption syndrome are the usual causes of vitamin B12 deficiency. Pernicious anemia is confirmed by the presence of intrinsic factor blocking antibody or abnormal results on the Schilling test. Patients with neuropsychiatric symptoms of vitamin B12 deficiency may have a normal Schilling test and no evidence of macrocytic anemia. In such patients, vitamin B12 deficiency is confirmed by determining serum levels of homocysteine and methylmalonic acid.
SN - 0002-838X
UR - https://www.unboundmedicine.com/medline/citation/2278533/The_spectrum_of_vitamin_B12_deficiency_
DB - PRIME
DP - Unbound Medicine
ER -