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A prospective study of cutaneous abnormalities in patients with chronic kidney disease.

Abstract

There are diverse ways in which the skin is affected by chronic kidney disease (CKD). Various specific and nonspecific skin abnormalities are observed in patients with CKD. The aim of the study was to document the prevalence of skin diseases that commonly occur in patients with CKD on medical treatment and dialysis. A total of 99 patients with CKD were examined for evidence of skin diseases. Ninety-six had at least one cutaneous abnormality attributable to CKD. The most prevalent finding was xerosis (66.7%), followed by pallor (45.45%), pruritus (43.4%), and cutaneous pigmentation (32.3%). Other cutaneous manifestations included dermatitis (27.27%); Kyrle's disease (17.17%); fungal (8.08%), bacterial (11.1%), and viral (5.05%) infections; purpura (10.1%); gynecomastia (4.04%); and yellow skin (5.05%). The common nail changes were half and half nails (36.36%) and onycholysis (13.13%). CKD is associated with various cutaneous abnormalities caused either by the disease or by treatment, the most common being xerosis and pruritus. The dermatologic complications can significantly impair the quality of life in certain individuals; therefore, earlier diagnosis and treatment is important to improve their quality of life.

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  • Authors+Show Affiliations

    ,

    Department of Dermatology, Christian Medical College and Hospital, Ludhiana, Punjab, India.

    ,

    Source

    Indian journal of nephrology 22:2 2012 Mar pg 116-20

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    22787313

    Citation

    Thomas, E A., et al. "A Prospective Study of Cutaneous Abnormalities in Patients With Chronic Kidney Disease." Indian Journal of Nephrology, vol. 22, no. 2, 2012, pp. 116-20.
    Thomas EA, Pawar B, Thomas A. A prospective study of cutaneous abnormalities in patients with chronic kidney disease. Indian J Nephrol. 2012;22(2):116-20.
    Thomas, E. A., Pawar, B., & Thomas, A. (2012). A prospective study of cutaneous abnormalities in patients with chronic kidney disease. Indian Journal of Nephrology, 22(2), pp. 116-20. doi:10.4103/0971-4065.97127.
    Thomas EA, Pawar B, Thomas A. A Prospective Study of Cutaneous Abnormalities in Patients With Chronic Kidney Disease. Indian J Nephrol. 2012;22(2):116-20. PubMed PMID: 22787313.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - A prospective study of cutaneous abnormalities in patients with chronic kidney disease. AU - Thomas,E A, AU - Pawar,B, AU - Thomas,A, PY - 2012/7/13/entrez PY - 2012/7/13/pubmed PY - 2012/7/13/medline KW - Chronic kidney disease KW - dialysis KW - uremic pruritus SP - 116 EP - 20 JF - Indian journal of nephrology JO - Indian J Nephrol VL - 22 IS - 2 N2 - There are diverse ways in which the skin is affected by chronic kidney disease (CKD). Various specific and nonspecific skin abnormalities are observed in patients with CKD. The aim of the study was to document the prevalence of skin diseases that commonly occur in patients with CKD on medical treatment and dialysis. A total of 99 patients with CKD were examined for evidence of skin diseases. Ninety-six had at least one cutaneous abnormality attributable to CKD. The most prevalent finding was xerosis (66.7%), followed by pallor (45.45%), pruritus (43.4%), and cutaneous pigmentation (32.3%). Other cutaneous manifestations included dermatitis (27.27%); Kyrle's disease (17.17%); fungal (8.08%), bacterial (11.1%), and viral (5.05%) infections; purpura (10.1%); gynecomastia (4.04%); and yellow skin (5.05%). The common nail changes were half and half nails (36.36%) and onycholysis (13.13%). CKD is associated with various cutaneous abnormalities caused either by the disease or by treatment, the most common being xerosis and pruritus. The dermatologic complications can significantly impair the quality of life in certain individuals; therefore, earlier diagnosis and treatment is important to improve their quality of life. SN - 1998-3662 UR - https://www.unboundmedicine.com/medline/citation/22787313/A_prospective_study_of_cutaneous_abnormalities_in_patients_with_chronic_kidney_disease_ L2 - http://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2012;volume=22;issue=2;spage=116;epage=120;aulast=Thomas DB - PRIME DP - Unbound Medicine ER -