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Diabetes mellitus in pancreatic cancer patients in the Czech Republic: sex differences.
Exp Diabetes Res 2012; 2012:414893ED

Abstract

AIMS

The prevalence of diabetes mellitus in pancreatic cancer patients and control subjects was compared.

METHODS

Retrospective evaluation of 182 pancreatic cancer patients and 135 controls. The presence of diabetes was evaluated and the time period between the diagnosis of diabetes and pancreatic cancer was assessed. A subanalysis based on patient sex was conducted.

RESULTS

Diabetes mellitus was present in 64 patients (35.2%) in pancreatic cancer group and in 27 patients (20.0%) in control group (χ(2) = 8.709; P = 0.003). In 18 patients (28.1% of diabetic pancreatic cancer patients) diabetes was new-onset. Diabetes was new-onset in 23.3% of females compared to 38.1% of males (χ(2) = 1.537; P = 0.215). The overall prevalence of diabetes was significantly higher among female pancreatic cancer patients (25% versus 43.9%; χ(2) = 7.070, P = 0.008), while diabetes prevalence was equally represented in the control group patients (22.1% versus 17.2%; χ(2) = 0.484, P = 0.487).

CONCLUSION

The prevalence of diabetes mellitus in study group of pancreatic cancer patients was significantly higher when compared to control group. Pancreatic cancer patients with diabetes were predominantly females, while diabetes was equally prevalent among sexes in the control group. Therefore, patient sex may play important role in the risk stratification.

Authors+Show Affiliations

Department of Internal Medicine and Gastroenterology, University Hospital and Faculty of Medicine, Masaryk University Brno, Jihlavska 20 62500 Brno, Czech Republic. jan.trna@seznam.czNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22792091

Citation

Trna, Jan, et al. "Diabetes Mellitus in Pancreatic Cancer Patients in the Czech Republic: Sex Differences." Experimental Diabetes Research, vol. 2012, 2012, p. 414893.
Trna J, Dítĕ P, Adamcová A, et al. Diabetes mellitus in pancreatic cancer patients in the Czech Republic: sex differences. Exp Diabetes Res. 2012;2012:414893.
Trna, J., Dítĕ, P., Adamcová, A., Crawford, B. J., & Hermanová, M. (2012). Diabetes mellitus in pancreatic cancer patients in the Czech Republic: sex differences. Experimental Diabetes Research, 2012, p. 414893. doi:10.1155/2012/414893.
Trna J, et al. Diabetes Mellitus in Pancreatic Cancer Patients in the Czech Republic: Sex Differences. Exp Diabetes Res. 2012;2012:414893. PubMed PMID: 22792091.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diabetes mellitus in pancreatic cancer patients in the Czech Republic: sex differences. AU - Trna,Jan, AU - Dítĕ,Petr, AU - Adamcová,Arona, AU - Crawford,Brianna J, AU - Hermanová,Markéta, Y1 - 2012/06/27/ PY - 2011/12/20/received PY - 2012/03/21/revised PY - 2012/05/08/accepted PY - 2012/7/14/entrez PY - 2012/7/14/pubmed PY - 2012/10/13/medline SP - 414893 EP - 414893 JF - Experimental diabetes research JO - Exp Diabetes Res VL - 2012 N2 - AIMS: The prevalence of diabetes mellitus in pancreatic cancer patients and control subjects was compared. METHODS: Retrospective evaluation of 182 pancreatic cancer patients and 135 controls. The presence of diabetes was evaluated and the time period between the diagnosis of diabetes and pancreatic cancer was assessed. A subanalysis based on patient sex was conducted. RESULTS: Diabetes mellitus was present in 64 patients (35.2%) in pancreatic cancer group and in 27 patients (20.0%) in control group (χ(2) = 8.709; P = 0.003). In 18 patients (28.1% of diabetic pancreatic cancer patients) diabetes was new-onset. Diabetes was new-onset in 23.3% of females compared to 38.1% of males (χ(2) = 1.537; P = 0.215). The overall prevalence of diabetes was significantly higher among female pancreatic cancer patients (25% versus 43.9%; χ(2) = 7.070, P = 0.008), while diabetes prevalence was equally represented in the control group patients (22.1% versus 17.2%; χ(2) = 0.484, P = 0.487). CONCLUSION: The prevalence of diabetes mellitus in study group of pancreatic cancer patients was significantly higher when compared to control group. Pancreatic cancer patients with diabetes were predominantly females, while diabetes was equally prevalent among sexes in the control group. Therefore, patient sex may play important role in the risk stratification. SN - 1687-5303 UR - https://www.unboundmedicine.com/medline/citation/22792091/Diabetes_mellitus_in_pancreatic_cancer_patients_in_the_Czech_Republic:_sex_differences_ L2 - https://dx.doi.org/10.1155/2012/414893 DB - PRIME DP - Unbound Medicine ER -