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Methamphetamine and amphetamine concentrations in postmortem rabbit tissues.
Forensic Sci Int. 1990 Nov; 48(1):39-47.FS

Abstract

The feasibility of detecting methamphetamine and its major metabolite, amphetamine, in postmortem tissues over a 2-year period was examined. It is important to determine if the abuse and toxic effects of drugs can be proved from evidence found in decayed, submerged, or stained tissue materials. The blood, urine, liver, skeletal muscle, skin and extremity bones from rabbits given methamphetamine intravenously were kept at room temperature, under 4 different conditions: sealed in a test tube, dried in the open air, submerged in tap water and stained on gauze. Methamphetamine was present in all the samples, with slight change in concentration in case of sealed and air dried tissues. Changes varied in bones kept in water. There were considerable decreases in methamphetamine in blood and urine stains. Despite long term storage, drug abuse and/or toxicity could be determined, in all tissues examined.

Authors+Show Affiliations

Department of Forensic Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2279720

Citation

Nagata, T, et al. "Methamphetamine and Amphetamine Concentrations in Postmortem Rabbit Tissues." Forensic Science International, vol. 48, no. 1, 1990, pp. 39-47.
Nagata T, Kimura K, Hara K, et al. Methamphetamine and amphetamine concentrations in postmortem rabbit tissues. Forensic Sci Int. 1990;48(1):39-47.
Nagata, T., Kimura, K., Hara, K., & Kudo, K. (1990). Methamphetamine and amphetamine concentrations in postmortem rabbit tissues. Forensic Science International, 48(1), 39-47.
Nagata T, et al. Methamphetamine and Amphetamine Concentrations in Postmortem Rabbit Tissues. Forensic Sci Int. 1990;48(1):39-47. PubMed PMID: 2279720.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Methamphetamine and amphetamine concentrations in postmortem rabbit tissues. AU - Nagata,T, AU - Kimura,K, AU - Hara,K, AU - Kudo,K, PY - 1990/11/1/pubmed PY - 1990/11/1/medline PY - 1990/11/1/entrez SP - 39 EP - 47 JF - Forensic science international JO - Forensic Sci. Int. VL - 48 IS - 1 N2 - The feasibility of detecting methamphetamine and its major metabolite, amphetamine, in postmortem tissues over a 2-year period was examined. It is important to determine if the abuse and toxic effects of drugs can be proved from evidence found in decayed, submerged, or stained tissue materials. The blood, urine, liver, skeletal muscle, skin and extremity bones from rabbits given methamphetamine intravenously were kept at room temperature, under 4 different conditions: sealed in a test tube, dried in the open air, submerged in tap water and stained on gauze. Methamphetamine was present in all the samples, with slight change in concentration in case of sealed and air dried tissues. Changes varied in bones kept in water. There were considerable decreases in methamphetamine in blood and urine stains. Despite long term storage, drug abuse and/or toxicity could be determined, in all tissues examined. SN - 0379-0738 UR - https://www.unboundmedicine.com/medline/citation/2279720/Methamphetamine_and_amphetamine_concentrations_in_postmortem_rabbit_tissues_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0379-0738(90)90270-9 DB - PRIME DP - Unbound Medicine ER -