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Metformin associated B12 deficiency.

Abstract

According to the ADA guidelines, metformin and lifestyle modifications are the first line therapies in the treatment of type 2 diabetes mellitus. Metformin does, however, cause vitamin B-12 malabsorption, which may increase the risk of developing vitamin B-12 deficiency--a clinically important and treatable condition. Here we report a case of 60 year old diabetic male presenting with clinical features of Vitamin B-12 deficiency on long term metformin therapy, which was confirmed on investigations. Patient showed symptomatic improvement with change in treatment.

Grapherence [↓5]

Authors+Show Affiliations

Kumthekar AA
,

Sumati Diabetes Clinic, Nashik 422002.

Gidwani HV
,
Kumthekar AB

Source

MeSH

Diabetes Mellitus, Type 2
Humans
Hydroxocobalamin
Hypoglycemic Agents
Malabsorption Syndromes
Male
Metformin
Middle Aged
Treatment Outcome
Vitamin B 12
Vitamin B 12 Deficiency
Vitamin B Complex

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22799121

Citation

Kumthekar, Anand Ajit, et al. "Metformin Associated B12 Deficiency." The Journal of the Association of Physicians of India, vol. 60, 2012, pp. 58-60.
Kumthekar AA, Gidwani HV, Kumthekar AB. Metformin associated B12 deficiency. J Assoc Physicians India. 2012;60:58-60.
Kumthekar, A. A., Gidwani, H. V., & Kumthekar, A. B. (2012). Metformin associated B12 deficiency. The Journal of the Association of Physicians of India, 60, pp. 58-60.
Kumthekar AA, Gidwani HV, Kumthekar AB. Metformin Associated B12 Deficiency. J Assoc Physicians India. 2012;60:58-60. PubMed PMID: 22799121.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Metformin associated B12 deficiency. AU - Kumthekar,Anand Ajit, AU - Gidwani,Hitesh Vinod, AU - Kumthekar,Ajit Bhaskar, PY - 2012/7/18/entrez PY - 2012/7/18/pubmed PY - 2012/8/8/medline SP - 58 EP - 60 JF - The Journal of the Association of Physicians of India JO - J Assoc Physicians India VL - 60 N2 - According to the ADA guidelines, metformin and lifestyle modifications are the first line therapies in the treatment of type 2 diabetes mellitus. Metformin does, however, cause vitamin B-12 malabsorption, which may increase the risk of developing vitamin B-12 deficiency--a clinically important and treatable condition. Here we report a case of 60 year old diabetic male presenting with clinical features of Vitamin B-12 deficiency on long term metformin therapy, which was confirmed on investigations. Patient showed symptomatic improvement with change in treatment. SN - 0004-5772 UR - https://www.unboundmedicine.com/medline/citation/22799121/Metformin_associated_B12_deficiency_ L2 - https://medlineplus.gov/diabetestype2.html DB - PRIME DP - Unbound Medicine ER -