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The antimicrobial effects of propolis collected in different regions in the Basque Country (Northern Spain).
World J Microbiol Biotechnol 2012; 28(4):1351-8WJ

Abstract

The antimicrobial activity of 19 propolis extracts prepared in different solvents (ethanol and propylene glycol) (EEP/PEP), was evaluated against some bacterial and fungal isolates using the agar-well diffusion method. It was verified that all the samples tested showed antimicrobial activity, although results varied considerably between samples. Results revealed that both types of propolis extracts showed highly sensitive antimicrobial action against Gram-positive bacteria and fungi at a concentration of 20% (Staphylococcus aureus, Streptococcus mutans, Candida albicans and Saccharomyces cerevisae) with a minimal inhibitory concentration (MIC) ranging from 0.5 to 1.5 mg/ml, with a moderate effect against Streptococcus pyogenes (MIC from 17 to 26 mg/ml). To our knowledge, this is the first study showing elevated antimicrobial activity against Gram-negative bacteria [Salmonella enterica (MIC from 0.6 to 1.4 mg/ml)] and lesser activity against Helicobacter pylori (MIC from 6 to 14 mg/ml), while Escherichia coli was resistant. This concluded that the Basque propolis had a strong and dose-dependent activity against most of the microbial strains tested, while database comparison revealed that phenolic substances were responsible for this inhibition, regardless of their geographical origin and the solvent employed for extraction. Statistical analysis showed no significant differences (P ≤ 0.05) between EEP and PEP extracts.

Authors+Show Affiliations

Research and Development of Nederland Co., P.O. Box 34, 08890, Viladecans, Spain. serrjosep@gmail.comNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22805915

Citation

Bonvehí, Josep Serra, and Arrate Lacalle Gutiérrez. "The Antimicrobial Effects of Propolis Collected in Different Regions in the Basque Country (Northern Spain)." World Journal of Microbiology & Biotechnology, vol. 28, no. 4, 2012, pp. 1351-8.
Bonvehí JS, Gutiérrez AL. The antimicrobial effects of propolis collected in different regions in the Basque Country (Northern Spain). World J Microbiol Biotechnol. 2012;28(4):1351-8.
Bonvehí, J. S., & Gutiérrez, A. L. (2012). The antimicrobial effects of propolis collected in different regions in the Basque Country (Northern Spain). World Journal of Microbiology & Biotechnology, 28(4), pp. 1351-8. doi:10.1007/s11274-011-0932-y.
Bonvehí JS, Gutiérrez AL. The Antimicrobial Effects of Propolis Collected in Different Regions in the Basque Country (Northern Spain). World J Microbiol Biotechnol. 2012;28(4):1351-8. PubMed PMID: 22805915.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The antimicrobial effects of propolis collected in different regions in the Basque Country (Northern Spain). AU - Bonvehí,Josep Serra, AU - Gutiérrez,Arrate Lacalle, Y1 - 2011/11/08/ PY - 2011/06/03/received PY - 2011/10/25/accepted PY - 2012/7/19/entrez PY - 2012/7/19/pubmed PY - 2013/2/12/medline SP - 1351 EP - 8 JF - World journal of microbiology & biotechnology JO - World J. Microbiol. Biotechnol. VL - 28 IS - 4 N2 - The antimicrobial activity of 19 propolis extracts prepared in different solvents (ethanol and propylene glycol) (EEP/PEP), was evaluated against some bacterial and fungal isolates using the agar-well diffusion method. It was verified that all the samples tested showed antimicrobial activity, although results varied considerably between samples. Results revealed that both types of propolis extracts showed highly sensitive antimicrobial action against Gram-positive bacteria and fungi at a concentration of 20% (Staphylococcus aureus, Streptococcus mutans, Candida albicans and Saccharomyces cerevisae) with a minimal inhibitory concentration (MIC) ranging from 0.5 to 1.5 mg/ml, with a moderate effect against Streptococcus pyogenes (MIC from 17 to 26 mg/ml). To our knowledge, this is the first study showing elevated antimicrobial activity against Gram-negative bacteria [Salmonella enterica (MIC from 0.6 to 1.4 mg/ml)] and lesser activity against Helicobacter pylori (MIC from 6 to 14 mg/ml), while Escherichia coli was resistant. This concluded that the Basque propolis had a strong and dose-dependent activity against most of the microbial strains tested, while database comparison revealed that phenolic substances were responsible for this inhibition, regardless of their geographical origin and the solvent employed for extraction. Statistical analysis showed no significant differences (P ≤ 0.05) between EEP and PEP extracts. SN - 1573-0972 UR - https://www.unboundmedicine.com/medline/citation/22805915/The_antimicrobial_effects_of_propolis_collected_in_different_regions_in_the_Basque_Country__Northern_Spain__ L2 - https://dx.doi.org/10.1007/s11274-011-0932-y DB - PRIME DP - Unbound Medicine ER -