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Diagnosis of common dermopathies in dialysis patients: a review and update.
Semin Dial 2012; 25(4):408-18SD

Abstract

Cutaneous abnormalities in patients with end-stage renal disease (ESRD) receiving hemodialysis or peritoneal dialysis may demonstrate signs of their underlying condition or reveal associated disease entities. While a thorough examination of the scalp, skin, mucosa, and nails is integral to establishing a diagnosis, certain conditions will resolve only with dialysis or improvement of their renal disease and others may not require or respond to treatment. Half and half nails, pruritus, xerosis, and cutaneous hyperpigmentation are common manifestations in ESRD. With hemodialysis, uremic frost is no longer prevalent in ESRD patients and ecchymoses have decreased in incidence. Acquired perforating dermatoses are seen in over one-tenth of hemodialysis patients. Metastatic calcinosis cutis and calciphylaxis are both rarely reported, although the latter is seen almost exclusively in the setting of hemodialysis. Diagnosis of nephrogenic systemic fibrosis has historically been challenging; as such, new diagnostic criteria have been proposed. Blood porphyrin profiles are needed to differentiate between porphyria cutanea tarda and pseudoporphyria. We will review and provide an update on the aforementioned common cutaneous manifestations of ESRD in patients receiving dialysis.

Authors+Show Affiliations

Department of Dermatology, Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22809004

Citation

Markova, Alina, et al. "Diagnosis of Common Dermopathies in Dialysis Patients: a Review and Update." Seminars in Dialysis, vol. 25, no. 4, 2012, pp. 408-18.
Markova A, Lester J, Wang J, et al. Diagnosis of common dermopathies in dialysis patients: a review and update. Semin Dial. 2012;25(4):408-18.
Markova, A., Lester, J., Wang, J., & Robinson-Bostom, L. (2012). Diagnosis of common dermopathies in dialysis patients: a review and update. Seminars in Dialysis, 25(4), pp. 408-18. doi:10.1111/j.1525-139X.2012.01109.x.
Markova A, et al. Diagnosis of Common Dermopathies in Dialysis Patients: a Review and Update. Semin Dial. 2012;25(4):408-18. PubMed PMID: 22809004.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis of common dermopathies in dialysis patients: a review and update. AU - Markova,Alina, AU - Lester,Jenna, AU - Wang,Joanne, AU - Robinson-Bostom,Leslie, PY - 2012/7/20/entrez PY - 2012/7/20/pubmed PY - 2013/1/9/medline SP - 408 EP - 18 JF - Seminars in dialysis JO - Semin Dial VL - 25 IS - 4 N2 - Cutaneous abnormalities in patients with end-stage renal disease (ESRD) receiving hemodialysis or peritoneal dialysis may demonstrate signs of their underlying condition or reveal associated disease entities. While a thorough examination of the scalp, skin, mucosa, and nails is integral to establishing a diagnosis, certain conditions will resolve only with dialysis or improvement of their renal disease and others may not require or respond to treatment. Half and half nails, pruritus, xerosis, and cutaneous hyperpigmentation are common manifestations in ESRD. With hemodialysis, uremic frost is no longer prevalent in ESRD patients and ecchymoses have decreased in incidence. Acquired perforating dermatoses are seen in over one-tenth of hemodialysis patients. Metastatic calcinosis cutis and calciphylaxis are both rarely reported, although the latter is seen almost exclusively in the setting of hemodialysis. Diagnosis of nephrogenic systemic fibrosis has historically been challenging; as such, new diagnostic criteria have been proposed. Blood porphyrin profiles are needed to differentiate between porphyria cutanea tarda and pseudoporphyria. We will review and provide an update on the aforementioned common cutaneous manifestations of ESRD in patients receiving dialysis. SN - 1525-139X UR - https://www.unboundmedicine.com/medline/citation/22809004/Diagnosis_of_common_dermopathies_in_dialysis_patients:_a_review_and_update_ L2 - https://doi.org/10.1111/j.1525-139X.2012.01109.x DB - PRIME DP - Unbound Medicine ER -