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Overview of trans fatty acids: biochemistry and health effects.
Diabetes Metab Syndr. 2011 Jul-Sep; 5(3):161-4.DM

Abstract

Trans fatty acids (TFA) are unsaturated fatty acids that contain at least one non-conjugated double bond in the trans configuration, resulting in a straighter shape. TFA present in our diet can either be industrially produced and ruminant or natural. The major process contributing to formation of industrial TFA is hydrogenation of vegetable oils. Thermal processes such as edible oil refining and frying also lead to the formation of TFA while, ruminant/natural TFA is formed in the rumen of ruminant animals through bio-hydrogenation. Industrial TFA poses severe effects on our health like cardiovascular problems, insulin resistance, infertility in women, compromised fetal development and cognitive decline. There are strict regulations for limiting/removing the TFA content from food supply across the world. However in India, there is scarcity of data on TFA content in foods and their consumption levels. Given the alarmingly rising trend of diabetes and cardiovascular disease in India, removal of TFA from the food supply along with generating awareness among the masses in this regard is of immense importance.

Authors+Show Affiliations

National Diabetes, Obesity and Cholesterol Diseases Foundation (N-DOC), SDA, New Delhi, India.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

22813572

Citation

Bhardwaj, Swati, et al. "Overview of Trans Fatty Acids: Biochemistry and Health Effects." Diabetes & Metabolic Syndrome, vol. 5, no. 3, 2011, pp. 161-4.
Bhardwaj S, Passi SJ, Misra A. Overview of trans fatty acids: biochemistry and health effects. Diabetes Metab Syndr. 2011;5(3):161-4.
Bhardwaj, S., Passi, S. J., & Misra, A. (2011). Overview of trans fatty acids: biochemistry and health effects. Diabetes & Metabolic Syndrome, 5(3), 161-4. https://doi.org/10.1016/j.dsx.2012.03.002
Bhardwaj S, Passi SJ, Misra A. Overview of Trans Fatty Acids: Biochemistry and Health Effects. Diabetes Metab Syndr. 2011;5(3):161-4. PubMed PMID: 22813572.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Overview of trans fatty acids: biochemistry and health effects. AU - Bhardwaj,Swati, AU - Passi,Santosh Jain, AU - Misra,Anoop, Y1 - 2012/05/01/ PY - 2012/7/21/entrez PY - 2012/7/21/pubmed PY - 2013/4/26/medline SP - 161 EP - 4 JF - Diabetes & metabolic syndrome JO - Diabetes Metab Syndr VL - 5 IS - 3 N2 - Trans fatty acids (TFA) are unsaturated fatty acids that contain at least one non-conjugated double bond in the trans configuration, resulting in a straighter shape. TFA present in our diet can either be industrially produced and ruminant or natural. The major process contributing to formation of industrial TFA is hydrogenation of vegetable oils. Thermal processes such as edible oil refining and frying also lead to the formation of TFA while, ruminant/natural TFA is formed in the rumen of ruminant animals through bio-hydrogenation. Industrial TFA poses severe effects on our health like cardiovascular problems, insulin resistance, infertility in women, compromised fetal development and cognitive decline. There are strict regulations for limiting/removing the TFA content from food supply across the world. However in India, there is scarcity of data on TFA content in foods and their consumption levels. Given the alarmingly rising trend of diabetes and cardiovascular disease in India, removal of TFA from the food supply along with generating awareness among the masses in this regard is of immense importance. SN - 1878-0334 UR - https://www.unboundmedicine.com/medline/citation/22813572/Overview_of_trans_fatty_acids:_biochemistry_and_health_effects_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1871-4021(12)00031-8 DB - PRIME DP - Unbound Medicine ER -