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High prevalence of sarcopenia and reduced leg muscle mass in Japanese patients immediately after a hip fracture.
Geriatr Gerontol Int 2013; 13(2):413-20GG

Abstract

AIM

Sarcopenia-related falls and fractures are becoming an emerging problem as a result of rapid aging worldwide. We aimed to investigate the prevalence of sarcopenia by estimating the muscle mass of the arms and legs of patients with and without hip fracture.

METHODS

This cross-sectional study examined 357 patients immediately after a hip fracture (the HF group) and in 2511 patients from an outpatient clinic who did not have a hip fracture (the NF group) at single institution in Japan. We carried out whole-body dual energy X-ray absorptiometry to analyze body composition with skeletal muscle mass index (SMI; lean mass/height(2)) and bone mineral density (BMD). We carried out stepwise logistic regression analysis to determine the factors associated with a hip fracture.

RESULTS

Lower appendicular SMI (P < 0.001), leg SMI (P < 0.001), and higher prevalence of sarcopenia (P < 0.001) were observed in the HF group after controlling for age and sex. The arm SMI was similar in both groups (P > 0.95). In multivariate analysis, the presence of sarcopenia, older age and lower BMD were associated with the occurrence of a hip fracture (OR 1.476, P = 0.002; OR 1.103, P < 0.001; OR 0.082, P < 0.001; respectively).

CONCLUSION

This study showed a higher prevalence of sarcopenia and more reduced leg muscle mass in patients after a hip fracture than in the outclinic patients who did not have hip fractures. The results imply sarcopenia can be a risk factor for a hip fracture.

Authors+Show Affiliations

Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan. hidat@med.nagoya-u.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22816427

Citation

Hida, Tetsuro, et al. "High Prevalence of Sarcopenia and Reduced Leg Muscle Mass in Japanese Patients Immediately After a Hip Fracture." Geriatrics & Gerontology International, vol. 13, no. 2, 2013, pp. 413-20.
Hida T, Ishiguro N, Shimokata H, et al. High prevalence of sarcopenia and reduced leg muscle mass in Japanese patients immediately after a hip fracture. Geriatr Gerontol Int. 2013;13(2):413-20.
Hida, T., Ishiguro, N., Shimokata, H., Sakai, Y., Matsui, Y., Takemura, M., ... Harada, A. (2013). High prevalence of sarcopenia and reduced leg muscle mass in Japanese patients immediately after a hip fracture. Geriatrics & Gerontology International, 13(2), pp. 413-20. doi:10.1111/j.1447-0594.2012.00918.x.
Hida T, et al. High Prevalence of Sarcopenia and Reduced Leg Muscle Mass in Japanese Patients Immediately After a Hip Fracture. Geriatr Gerontol Int. 2013;13(2):413-20. PubMed PMID: 22816427.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - High prevalence of sarcopenia and reduced leg muscle mass in Japanese patients immediately after a hip fracture. AU - Hida,Tetsuro, AU - Ishiguro,Naoki, AU - Shimokata,Hiroshi, AU - Sakai,Yoshihito, AU - Matsui,Yasumoto, AU - Takemura,Marie, AU - Terabe,Yasuto, AU - Harada,Atsushi, Y1 - 2012/07/23/ PY - 2012/7/24/entrez PY - 2012/7/24/pubmed PY - 2013/11/6/medline SP - 413 EP - 20 JF - Geriatrics & gerontology international JO - Geriatr Gerontol Int VL - 13 IS - 2 N2 - AIM: Sarcopenia-related falls and fractures are becoming an emerging problem as a result of rapid aging worldwide. We aimed to investigate the prevalence of sarcopenia by estimating the muscle mass of the arms and legs of patients with and without hip fracture. METHODS: This cross-sectional study examined 357 patients immediately after a hip fracture (the HF group) and in 2511 patients from an outpatient clinic who did not have a hip fracture (the NF group) at single institution in Japan. We carried out whole-body dual energy X-ray absorptiometry to analyze body composition with skeletal muscle mass index (SMI; lean mass/height(2)) and bone mineral density (BMD). We carried out stepwise logistic regression analysis to determine the factors associated with a hip fracture. RESULTS: Lower appendicular SMI (P < 0.001), leg SMI (P < 0.001), and higher prevalence of sarcopenia (P < 0.001) were observed in the HF group after controlling for age and sex. The arm SMI was similar in both groups (P > 0.95). In multivariate analysis, the presence of sarcopenia, older age and lower BMD were associated with the occurrence of a hip fracture (OR 1.476, P = 0.002; OR 1.103, P < 0.001; OR 0.082, P < 0.001; respectively). CONCLUSION: This study showed a higher prevalence of sarcopenia and more reduced leg muscle mass in patients after a hip fracture than in the outclinic patients who did not have hip fractures. The results imply sarcopenia can be a risk factor for a hip fracture. SN - 1447-0594 UR - https://www.unboundmedicine.com/medline/citation/22816427/High_prevalence_of_sarcopenia_and_reduced_leg_muscle_mass_in_Japanese_patients_immediately_after_a_hip_fracture_ L2 - https://doi.org/10.1111/j.1447-0594.2012.00918.x DB - PRIME DP - Unbound Medicine ER -