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The association of consumption of fruits/vegetables with decreased risk of glaucoma among older African-American women in the study of osteoporotic fractures.

Abstract

PURPOSE

To explore the association between consumption of fruits and vegetables and the presence of glaucoma in older African-American women.

DESIGN

Cross-sectional study.

METHODS

Disc photographs and suprathreshold visual fields were obtained from the 662 African-American participants in the Study of Osteoporotic Fractures. Masked, trained readers graded all discs, and 2 glaucoma specialists reviewed photographs and visual fields. The Block Food Frequency Questionnaire assessed food consumption. Relationships between selected fruit/vegetable/nutrient consumption and glaucoma were evaluated using logistic regression models after adjusting for potential confounders.

RESULTS

After excluding women missing Food Frequency Questionnaire and disc data, 584 African-American women (88.2% of total African-American cohort) were included. Glaucoma was diagnosed in at least 1 eye in 77 subjects (13%). Women who ate 3 or more servings/day of fruits/fruit juices were 79% (odds ratio [OR] = 0.21; 95% confidence interval [CI]: 0.08-0.60) less likely to have glaucoma than women who ate less than 1 serving/day. Women who consumed more than 2 servings/week of fresh oranges (OR = 0.18; 95% CI: 0.06-0.51) and peaches (OR = 0.30; 95% CI: 0.13-0.67) had a decreased odds of glaucoma compared to those consuming less than 1 serving/week. For vegetables, >1 serving/week compared to ≤1 serving/month of collard greens/kale decreased the odds of glaucoma by 57% (OR = 0.43; 95% CI: 0.21-0.85). There was a protective trend against glaucoma in those consuming more fruit/fruit juices (P = .023), fresh oranges (P = .002), fresh peaches (P = .002), and collard greens/kale (P = .014). Higher consumption of carrots (P = .061) and spinach (P = .094) also showed some associations. Individual nutrient intake from food sources found protective trends with higher intakes of vitamin A (P = .011), vitamin C (P = .018), and α-carotene (P = .021), and close to statistically significant trends with β-carotene (P = .052), folate (P = .056), and lutein/zeaxanthin (P = .077).

CONCLUSION

Higher intake of certain fruits and vegetables high in vitamins A and C and carotenoids may be associated with a decreased likelihood of glaucoma in older African-American women. Randomized controlled trials are needed to determine whether the intake of specific nutrients changes the risk of glaucoma.

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  • Authors+Show Affiliations

    ,

    Department of Ophthalmology, University of California, Los Angeles, USA.

    , , , , , , ,

    Source

    American journal of ophthalmology 154:4 2012 Oct pg 635-44

    MeSH

    African Americans
    Aged
    Aged, 80 and over
    Antioxidants
    Cross-Sectional Studies
    Diet
    Diet Surveys
    Female
    Fractures, Bone
    Fruit
    Glaucoma
    Humans
    Odds Ratio
    Osteoporosis, Postmenopausal
    Risk Factors
    Surveys and Questionnaires
    United States
    Vegetables
    Visual Fields
    Women's Health

    Pub Type(s)

    Journal Article
    Multicenter Study
    Research Support, N.I.H., Extramural
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    22818906

    Citation

    Giaconi, Joann A., et al. "The Association of Consumption of Fruits/vegetables With Decreased Risk of Glaucoma Among Older African-American Women in the Study of Osteoporotic Fractures." American Journal of Ophthalmology, vol. 154, no. 4, 2012, pp. 635-44.
    Giaconi JA, Yu F, Stone KL, et al. The association of consumption of fruits/vegetables with decreased risk of glaucoma among older African-American women in the study of osteoporotic fractures. Am J Ophthalmol. 2012;154(4):635-44.
    Giaconi, J. A., Yu, F., Stone, K. L., Pedula, K. L., Ensrud, K. E., Cauley, J. A., ... Coleman, A. L. (2012). The association of consumption of fruits/vegetables with decreased risk of glaucoma among older African-American women in the study of osteoporotic fractures. American Journal of Ophthalmology, 154(4), pp. 635-44. doi:10.1016/j.ajo.2012.03.048.
    Giaconi JA, et al. The Association of Consumption of Fruits/vegetables With Decreased Risk of Glaucoma Among Older African-American Women in the Study of Osteoporotic Fractures. Am J Ophthalmol. 2012;154(4):635-44. PubMed PMID: 22818906.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The association of consumption of fruits/vegetables with decreased risk of glaucoma among older African-American women in the study of osteoporotic fractures. AU - Giaconi,Joann A, AU - Yu,Fei, AU - Stone,Katie L, AU - Pedula,Kathryn L, AU - Ensrud,Kristine E, AU - Cauley,Jane A, AU - Hochberg,Marc C, AU - Coleman,Anne L, AU - ,, Y1 - 2012/07/20/ PY - 2011/12/09/received PY - 2012/03/29/revised PY - 2012/03/30/accepted PY - 2012/7/24/entrez PY - 2012/7/24/pubmed PY - 2012/12/14/medline SP - 635 EP - 44 JF - American journal of ophthalmology JO - Am. J. Ophthalmol. VL - 154 IS - 4 N2 - PURPOSE: To explore the association between consumption of fruits and vegetables and the presence of glaucoma in older African-American women. DESIGN: Cross-sectional study. METHODS: Disc photographs and suprathreshold visual fields were obtained from the 662 African-American participants in the Study of Osteoporotic Fractures. Masked, trained readers graded all discs, and 2 glaucoma specialists reviewed photographs and visual fields. The Block Food Frequency Questionnaire assessed food consumption. Relationships between selected fruit/vegetable/nutrient consumption and glaucoma were evaluated using logistic regression models after adjusting for potential confounders. RESULTS: After excluding women missing Food Frequency Questionnaire and disc data, 584 African-American women (88.2% of total African-American cohort) were included. Glaucoma was diagnosed in at least 1 eye in 77 subjects (13%). Women who ate 3 or more servings/day of fruits/fruit juices were 79% (odds ratio [OR] = 0.21; 95% confidence interval [CI]: 0.08-0.60) less likely to have glaucoma than women who ate less than 1 serving/day. Women who consumed more than 2 servings/week of fresh oranges (OR = 0.18; 95% CI: 0.06-0.51) and peaches (OR = 0.30; 95% CI: 0.13-0.67) had a decreased odds of glaucoma compared to those consuming less than 1 serving/week. For vegetables, >1 serving/week compared to ≤1 serving/month of collard greens/kale decreased the odds of glaucoma by 57% (OR = 0.43; 95% CI: 0.21-0.85). There was a protective trend against glaucoma in those consuming more fruit/fruit juices (P = .023), fresh oranges (P = .002), fresh peaches (P = .002), and collard greens/kale (P = .014). Higher consumption of carrots (P = .061) and spinach (P = .094) also showed some associations. Individual nutrient intake from food sources found protective trends with higher intakes of vitamin A (P = .011), vitamin C (P = .018), and α-carotene (P = .021), and close to statistically significant trends with β-carotene (P = .052), folate (P = .056), and lutein/zeaxanthin (P = .077). CONCLUSION: Higher intake of certain fruits and vegetables high in vitamins A and C and carotenoids may be associated with a decreased likelihood of glaucoma in older African-American women. Randomized controlled trials are needed to determine whether the intake of specific nutrients changes the risk of glaucoma. SN - 1879-1891 UR - https://www.unboundmedicine.com/medline/citation/22818906/The_association_of_consumption_of_fruits/vegetables_with_decreased_risk_of_glaucoma_among_older_African_American_women_in_the_study_of_osteoporotic_fractures_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(12)00262-0 DB - PRIME DP - Unbound Medicine ER -