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Iodine-induced thyroid dysfunction.

Abstract

PURPOSE OF REVIEW

To summarize the mechanisms of iodine-induced hypothyroidism and hyperthyroidism, identify the risk factors for thyroid dysfunction following an iodine load, and summarize the major sources of excess iodine exposure.

RECENT FINDINGS

Excess iodine is generally well tolerated, but individuals with underlying thyroid disease or other risk factors may be susceptible to iodine-induced thyroid dysfunction following acute or chronic exposure. Sources of increased iodine exposure include the global public health efforts of iodine supplementation, the escalating use of iodinated contrast radiologic studies, amiodarone administration in vulnerable patients, excess seaweed consumption, and various miscellaneous sources.

SUMMARY

Iodine-induced thyroid dysfunction may be subclinical or overt. Recognition of the association between iodine excess and iodine-induced hypothyroidism or hyperthyroidism is important in the differential diagnosis of patients who present without a known cause of thyroid dysfunction.

Authors+Show Affiliations

Section of Endocrinology, Diabetes, and Nutrition, Boston University School of Medicine, Boston, Massachusetts 02118, USA. angela.leung@bmc.orgNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Review

Language

eng

PubMed ID

22820214

Citation

Leung, Angela M., and Lewis E. Braverman. "Iodine-induced Thyroid Dysfunction." Current Opinion in Endocrinology, Diabetes, and Obesity, vol. 19, no. 5, 2012, pp. 414-9.
Leung AM, Braverman LE. Iodine-induced thyroid dysfunction. Curr Opin Endocrinol Diabetes Obes. 2012;19(5):414-9.
Leung, A. M., & Braverman, L. E. (2012). Iodine-induced thyroid dysfunction. Current Opinion in Endocrinology, Diabetes, and Obesity, 19(5), pp. 414-9. doi:10.1097/MED.0b013e3283565bb2.
Leung AM, Braverman LE. Iodine-induced Thyroid Dysfunction. Curr Opin Endocrinol Diabetes Obes. 2012;19(5):414-9. PubMed PMID: 22820214.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Iodine-induced thyroid dysfunction. AU - Leung,Angela M, AU - Braverman,Lewis E, PY - 2012/7/24/entrez PY - 2012/7/24/pubmed PY - 2013/1/16/medline SP - 414 EP - 9 JF - Current opinion in endocrinology, diabetes, and obesity JO - Curr Opin Endocrinol Diabetes Obes VL - 19 IS - 5 N2 - PURPOSE OF REVIEW: To summarize the mechanisms of iodine-induced hypothyroidism and hyperthyroidism, identify the risk factors for thyroid dysfunction following an iodine load, and summarize the major sources of excess iodine exposure. RECENT FINDINGS: Excess iodine is generally well tolerated, but individuals with underlying thyroid disease or other risk factors may be susceptible to iodine-induced thyroid dysfunction following acute or chronic exposure. Sources of increased iodine exposure include the global public health efforts of iodine supplementation, the escalating use of iodinated contrast radiologic studies, amiodarone administration in vulnerable patients, excess seaweed consumption, and various miscellaneous sources. SUMMARY: Iodine-induced thyroid dysfunction may be subclinical or overt. Recognition of the association between iodine excess and iodine-induced hypothyroidism or hyperthyroidism is important in the differential diagnosis of patients who present without a known cause of thyroid dysfunction. SN - 1752-2978 UR - https://www.unboundmedicine.com/medline/citation/22820214/Iodine_induced_thyroid_dysfunction_ L2 - http://Insights.ovid.com/pubmed?pmid=22820214 DB - PRIME DP - Unbound Medicine ER -