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CNS toxoplasmosis presenting with obstructive hydrocephalus in patients of retroviral disease--a case series.
Med J Malaysia 2012; 67(2):214-6MJ

Abstract

CNS toxoplasmosis presenting as hydrocephalus is a very rare entity. We present three cases of HIV positive patients whose brain imaging revealed hydrocephalus and who improved with anti toxoplasma medication along with intravenous steroids and did not require any CSF shunting procedures. The mechanism of hydrocephalus in CNS toxoplasmosis is usually due to compression of CSF outflow pathway by ring enhancing lesions but even in their absence hydrocephalus can be rarely seen due to ventriculitis. Hence in HIV positive patients with unexplained hydrocephalus CNS toxoplasmosis should be considered and such patients if started on treatment early have a good prognosis without requiring neurosurgical intervention.

Authors+Show Affiliations

Medical College (affiliated to Manipal University), Pediatrics, KMC Hospital, N G Road, Attavar, Mangalore, Karnataka 575001 India.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22822648

Citation

Basavaprabhu, A, et al. "CNS Toxoplasmosis Presenting With Obstructive Hydrocephalus in Patients of Retroviral Disease--a Case Series." The Medical Journal of Malaysia, vol. 67, no. 2, 2012, pp. 214-6.
Basavaprabhu A, Soundarya M, Deepak M, et al. CNS toxoplasmosis presenting with obstructive hydrocephalus in patients of retroviral disease--a case series. Med J Malaysia. 2012;67(2):214-6.
Basavaprabhu, A., Soundarya, M., Deepak, M., & Satish, R. (2012). CNS toxoplasmosis presenting with obstructive hydrocephalus in patients of retroviral disease--a case series. The Medical Journal of Malaysia, 67(2), pp. 214-6.
Basavaprabhu A, et al. CNS Toxoplasmosis Presenting With Obstructive Hydrocephalus in Patients of Retroviral Disease--a Case Series. Med J Malaysia. 2012;67(2):214-6. PubMed PMID: 22822648.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - CNS toxoplasmosis presenting with obstructive hydrocephalus in patients of retroviral disease--a case series. AU - Basavaprabhu,A, AU - Soundarya,M, AU - Deepak,M, AU - Satish,R, PY - 2012/7/25/entrez PY - 2012/7/25/pubmed PY - 2012/9/21/medline SP - 214 EP - 6 JF - The Medical journal of Malaysia JO - Med. J. Malaysia VL - 67 IS - 2 N2 - CNS toxoplasmosis presenting as hydrocephalus is a very rare entity. We present three cases of HIV positive patients whose brain imaging revealed hydrocephalus and who improved with anti toxoplasma medication along with intravenous steroids and did not require any CSF shunting procedures. The mechanism of hydrocephalus in CNS toxoplasmosis is usually due to compression of CSF outflow pathway by ring enhancing lesions but even in their absence hydrocephalus can be rarely seen due to ventriculitis. Hence in HIV positive patients with unexplained hydrocephalus CNS toxoplasmosis should be considered and such patients if started on treatment early have a good prognosis without requiring neurosurgical intervention. SN - 0300-5283 UR - https://www.unboundmedicine.com/medline/citation/22822648/CNS_toxoplasmosis_presenting_with_obstructive_hydrocephalus_in_patients_of_retroviral_disease__a_case_series_ L2 - http://www.e-mjm.org/2012/v67n2/CNS-toxoplasmosis.pdf DB - PRIME DP - Unbound Medicine ER -