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Dietary factors and fluctuating levels of melatonin.
Food Nutr Res. 2012; 56FN

Abstract

Melatonin is secreted principally by the pineal gland and mainly at nighttime. The primary physiological function is to convey information of the daily cycle of light and darkness to the body. In addition, it may have other health-related functions. Melatonin is synthesized from tryptophan, an essential dietary amino acid. It has been demonstrated that some nutritional factors, such as intake of vegetables, caffeine, and some vitamins and minerals, could modify melatonin production but with less intensity than light, the most dominant synchronizer of melatonin production. This review will focus on the nutritional factors apart from the intake of tryptophan that affect melatonin levels in humans. Overall, foods containing melatonin or promoting the synthesis of it by impacting the availability of tryptophan, as well those containing vitamins and minerals which are needed as co-factors and activators in the synthesis of melatonin, may modulate the levels of melatonin. Even so, the influence of daytime diet on the synthesis of nocturnal melatonin is limited, however, the influence of the diet seems to be more obvious on the daytime levels.

Authors+Show Affiliations

Institute of Biomedicine, Pharmacology, Medical Nutrition Physiology, University of Helsinki, Helsinki, Finland.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22826693

Citation

Peuhkuri, Katri, et al. "Dietary Factors and Fluctuating Levels of Melatonin." Food & Nutrition Research, vol. 56, 2012.
Peuhkuri K, Sihvola N, Korpela R. Dietary factors and fluctuating levels of melatonin. Food Nutr Res. 2012;56.
Peuhkuri, K., Sihvola, N., & Korpela, R. (2012). Dietary factors and fluctuating levels of melatonin. Food & Nutrition Research, 56. https://doi.org/10.3402/fnr.v56i0.17252
Peuhkuri K, Sihvola N, Korpela R. Dietary Factors and Fluctuating Levels of Melatonin. Food Nutr Res. 2012;56 PubMed PMID: 22826693.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary factors and fluctuating levels of melatonin. AU - Peuhkuri,Katri, AU - Sihvola,Nora, AU - Korpela,Riitta, Y1 - 2012/07/20/ PY - 2012/01/23/received PY - 2012/05/03/revised PY - 2012/06/12/accepted PY - 2012/7/25/entrez PY - 2012/7/25/pubmed PY - 2012/7/25/medline KW - 6-sulphatoxymelatonin KW - B vitamins KW - alcohol KW - diet KW - melatonin KW - vegetable JF - Food & nutrition research JO - Food Nutr Res VL - 56 N2 - Melatonin is secreted principally by the pineal gland and mainly at nighttime. The primary physiological function is to convey information of the daily cycle of light and darkness to the body. In addition, it may have other health-related functions. Melatonin is synthesized from tryptophan, an essential dietary amino acid. It has been demonstrated that some nutritional factors, such as intake of vegetables, caffeine, and some vitamins and minerals, could modify melatonin production but with less intensity than light, the most dominant synchronizer of melatonin production. This review will focus on the nutritional factors apart from the intake of tryptophan that affect melatonin levels in humans. Overall, foods containing melatonin or promoting the synthesis of it by impacting the availability of tryptophan, as well those containing vitamins and minerals which are needed as co-factors and activators in the synthesis of melatonin, may modulate the levels of melatonin. Even so, the influence of daytime diet on the synthesis of nocturnal melatonin is limited, however, the influence of the diet seems to be more obvious on the daytime levels. SN - 1654-661X UR - https://www.unboundmedicine.com/medline/citation/22826693/full_citation L2 - https://doi.org/10.3402/fnr.v56i0.17252 DB - PRIME DP - Unbound Medicine ER -
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