Tags

Type your tag names separated by a space and hit enter

Comparison of three fluid regimens for preloading in elective caesarean section under spinal anaesthesia.
Mymensingh Med J 2012; 21(3):533-40MM

Abstract

The most common problem associated with subarachnoid block (SAB) for caesarean section remains the rapid onset of profound hypotension. This study was designed to compare the incidence of hypotension after preloading with Ringer's Lactate, Hydroxyethylstarch and combination prior to SAB in caesarean section. Ninety non-labouring ASA grade 1 and 2, aged 20-35 years, weight and height was 45-60kg and 153-165cm respectively divided randomly into three groups. Group-RL received Ringer's Lactate 20ml/kg as preloading fluid. Group-H received Hydroxyethylstarch-6% 8ml/kg and Group-RLH received preloading fluid with combination of Ringer's Lactate 10ml/kg and Hydroxyethylstarch-6% 4ml/kg. Blood pressure (Systolic, Diastolic & Mean arterial pressure) was measured every 5 minute for 20 minute and every 10 minutes thereafter. Hypotension was less in Group-RLH (6.7%) whereas in Group-H and Group-RL hypotension was 20% and 47.7% respectively. Systolic blood pressure decreased significantly in all three groups. But the decreasing was less in Group-RLH than other two groups. Less IV fluid was required in Group-RLH (403ml) and Group-H (577ml) in comparison to Group-RL (1032ml) to prevent and treat peroperative hypotension. No ephedrine was needed in Group-RLH. Variation in Pulse rate was not significant in Group-RLH (p=0.061). But in other two groups it was highly significant (Group RL p≤0.001 and Group H p=0.004). There was no significant difference in neonatal outcome between three groups. Preloading with low volume colloid (4ml/kg) plus crystalloid (10ml/kg) is superior to crystalloid or colloid alone.

Authors+Show Affiliations

Department of Anaesthesiology, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam. drkamrul@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

22828556

Citation

Hasan, A B., et al. "Comparison of Three Fluid Regimens for Preloading in Elective Caesarean Section Under Spinal Anaesthesia." Mymensingh Medical Journal : MMJ, vol. 21, no. 3, 2012, pp. 533-40.
Hasan AB, Mondal MK, Badruddoza NM, et al. Comparison of three fluid regimens for preloading in elective caesarean section under spinal anaesthesia. Mymensingh Med J. 2012;21(3):533-40.
Hasan, A. B., Mondal, M. K., Badruddoza, N. M., Bhowmick, D. K., Islam, M. S., Akhtaruzzaman, K. M., & Islam, M. M. (2012). Comparison of three fluid regimens for preloading in elective caesarean section under spinal anaesthesia. Mymensingh Medical Journal : MMJ, 21(3), pp. 533-40.
Hasan AB, et al. Comparison of Three Fluid Regimens for Preloading in Elective Caesarean Section Under Spinal Anaesthesia. Mymensingh Med J. 2012;21(3):533-40. PubMed PMID: 22828556.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of three fluid regimens for preloading in elective caesarean section under spinal anaesthesia. AU - Hasan,A B, AU - Mondal,M K, AU - Badruddoza,N M, AU - Bhowmick,D K, AU - Islam,M S, AU - Akhtaruzzaman,K M, AU - Islam,M M, PY - 2012/7/26/entrez PY - 2012/7/26/pubmed PY - 2012/12/12/medline SP - 533 EP - 40 JF - Mymensingh medical journal : MMJ JO - Mymensingh Med J VL - 21 IS - 3 N2 - The most common problem associated with subarachnoid block (SAB) for caesarean section remains the rapid onset of profound hypotension. This study was designed to compare the incidence of hypotension after preloading with Ringer's Lactate, Hydroxyethylstarch and combination prior to SAB in caesarean section. Ninety non-labouring ASA grade 1 and 2, aged 20-35 years, weight and height was 45-60kg and 153-165cm respectively divided randomly into three groups. Group-RL received Ringer's Lactate 20ml/kg as preloading fluid. Group-H received Hydroxyethylstarch-6% 8ml/kg and Group-RLH received preloading fluid with combination of Ringer's Lactate 10ml/kg and Hydroxyethylstarch-6% 4ml/kg. Blood pressure (Systolic, Diastolic & Mean arterial pressure) was measured every 5 minute for 20 minute and every 10 minutes thereafter. Hypotension was less in Group-RLH (6.7%) whereas in Group-H and Group-RL hypotension was 20% and 47.7% respectively. Systolic blood pressure decreased significantly in all three groups. But the decreasing was less in Group-RLH than other two groups. Less IV fluid was required in Group-RLH (403ml) and Group-H (577ml) in comparison to Group-RL (1032ml) to prevent and treat peroperative hypotension. No ephedrine was needed in Group-RLH. Variation in Pulse rate was not significant in Group-RLH (p=0.061). But in other two groups it was highly significant (Group RL p≤0.001 and Group H p=0.004). There was no significant difference in neonatal outcome between three groups. Preloading with low volume colloid (4ml/kg) plus crystalloid (10ml/kg) is superior to crystalloid or colloid alone. SN - 1022-4742 UR - https://www.unboundmedicine.com/medline/citation/22828556/Comparison_of_three_fluid_regimens_for_preloading_in_elective_caesarean_section_under_spinal_anaesthesia_ L2 - https://medlineplus.gov/cesareansection.html DB - PRIME DP - Unbound Medicine ER -