TY - JOUR T1 - Simultaneous determination of ascorbic acid, dopamine, uric acid and tryptophan on gold nanoparticles/overoxidized-polyimidazole composite modified glassy carbon electrode. AU - Wang,Cun, AU - Yuan,Ruo, AU - Chai,Yaqin, AU - Chen,Shihong, AU - Hu,Fangxin, AU - Zhang,Meihe, Y1 - 2012/07/04/ PY - 2012/03/13/received PY - 2012/06/18/revised PY - 2012/06/19/accepted PY - 2012/7/31/entrez PY - 2012/7/31/pubmed PY - 2013/3/19/medline SP - 15 EP - 20 JF - Analytica chimica acta JO - Anal Chim Acta VL - 741 N2 - A novel electrode was developed through electrodepositing gold nanoparticles (GNPs) on overoxidized-polyimidazole (PImox) film modified glassy carbon electrode (GCE). The combination of GNPs and the PImox film endowed the GNPs/PImox/GCE with good biological compatibility, high selectivity and sensitivity and excellent electrochemical catalytic activities towards ascorbic acid (AA), dopamine (DA), uric acid (UA) and tryptophan (Trp). In the fourfold co-existence system, the peak separations between AA-DA, DA-UA and UA-Trp were large up to 186, 165 and 285 mV, respectively. The calibration curves for AA, DA and UA were obtained in the range of 210.0-1010.0 μM, 5.0-268.0 μM and 6.0-486.0 μM with detection limits (S/N=3) of 2.0 μM, 0.08 μM and 0.5 μM, respectively. Two linear calibrations for Trp were obtained over ranges of 3.0-34.0 μM and 84.0-464.0 μM with detection limit (S/N=3) of 0.7 μM. In addition, the modified electrode was applied to detect AA, DA, UA and Trp in samples using standard addition method with satisfactory results. SN - 1873-4324 UR - https://www.unboundmedicine.com/medline/citation/22840700/Simultaneous_determination_of_ascorbic_acid_dopamine_uric_acid_and_tryptophan_on_gold_nanoparticles/overoxidized_polyimidazole_composite_modified_glassy_carbon_electrode_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0003-2670(12)00965-8 DB - PRIME DP - Unbound Medicine ER -