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Leptospirosis and Weil's disease in the UK.
QJM. 2012 Dec; 105(12):1151-62.QJM

Abstract

The recent high-profile death of a British Olympic rower from leptospirosis has raised awareness to this uncommon but potentially fatal disease. The re-emergence of the disease abroad is well documented in the literature, but less is known about cases in the UK. The increase in participation in water sports, foreign travel and often a combination of the two, has increased the exposure of tourists subsequently returning to the UK from areas of high prevalence. Leptospirosis is a zoonotic infection. The bacteria are shed in the urine of animals to the environment from where humans are infected by incidental hosts. There is a wide spectrum of severity of symptoms, from a self-limiting febrile illness to fatal pulmonary haemorrhage, renal or liver failure. It is thought that cases remain unrecognized every year in the UK, largely due to the mild nature of symptoms and the wide differential for febrile illness and partly due to lack of awareness among clinicians. This review examines the epidemiology of leptospirosis in the UK, over the period 2006-10, the clinical features, diagnostic techniques and treatment.

Authors+Show Affiliations

Department of Cardiology, Hillingdon Hospital, Pield Heath Road, Uxbridge, Middlesex, UB8 3NN, UK.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22843698

Citation

Forbes, A E., et al. "Leptospirosis and Weil's Disease in the UK." QJM : Monthly Journal of the Association of Physicians, vol. 105, no. 12, 2012, pp. 1151-62.
Forbes AE, Zochowski WJ, Dubrey SW, et al. Leptospirosis and Weil's disease in the UK. QJM. 2012;105(12):1151-62.
Forbes, A. E., Zochowski, W. J., Dubrey, S. W., & Sivaprakasam, V. (2012). Leptospirosis and Weil's disease in the UK. QJM : Monthly Journal of the Association of Physicians, 105(12), 1151-62. https://doi.org/10.1093/qjmed/hcs145
Forbes AE, et al. Leptospirosis and Weil's Disease in the UK. QJM. 2012;105(12):1151-62. PubMed PMID: 22843698.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Leptospirosis and Weil's disease in the UK. AU - Forbes,A E, AU - Zochowski,W J, AU - Dubrey,S W, AU - Sivaprakasam,V, Y1 - 2012/07/27/ PY - 2012/7/31/entrez PY - 2012/7/31/pubmed PY - 2013/6/7/medline SP - 1151 EP - 62 JF - QJM : monthly journal of the Association of Physicians JO - QJM VL - 105 IS - 12 N2 - The recent high-profile death of a British Olympic rower from leptospirosis has raised awareness to this uncommon but potentially fatal disease. The re-emergence of the disease abroad is well documented in the literature, but less is known about cases in the UK. The increase in participation in water sports, foreign travel and often a combination of the two, has increased the exposure of tourists subsequently returning to the UK from areas of high prevalence. Leptospirosis is a zoonotic infection. The bacteria are shed in the urine of animals to the environment from where humans are infected by incidental hosts. There is a wide spectrum of severity of symptoms, from a self-limiting febrile illness to fatal pulmonary haemorrhage, renal or liver failure. It is thought that cases remain unrecognized every year in the UK, largely due to the mild nature of symptoms and the wide differential for febrile illness and partly due to lack of awareness among clinicians. This review examines the epidemiology of leptospirosis in the UK, over the period 2006-10, the clinical features, diagnostic techniques and treatment. SN - 1460-2393 UR - https://www.unboundmedicine.com/medline/citation/22843698/Leptospirosis_and_Weil's_disease_in_the_UK_ L2 - https://academic.oup.com/qjmed/article-lookup/doi/10.1093/qjmed/hcs145 DB - PRIME DP - Unbound Medicine ER -