Tags

Type your tag names separated by a space and hit enter

Genetic testing by cancer site: colon (polyposis syndromes).
Cancer J. 2012 Jul-Aug; 18(4):328-33.CJ

Abstract

Hereditary colonic polyposis conditions are all characterized by high rates of cancer, but they have diverse phenotypes, genetic heterogeneity, and assorted inheritance patterns. The most well known of these conditions include familial adenomatous polyposis, attenuated familial adenomatous polyposis, MUTYH (MutY human homolog)-associated polyposis, Peutz-Jeghers syndrome, juvenile polyposis syndrome, and Cowden syndrome. Early recognition of these conditions is not only vital for management in affected individuals, but also for prevention and early detection in at-risk relatives. Reviewed here are the genetic testing strategies for colonic polyposis, as well as an overview of characteristic features and management considerations for these syndromes.

Authors+Show Affiliations

Huntsman Cancer Institute, Salt Lake City, UT 84112, USA. Kory.Jasperson@hci.utah.edu

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

22846733

Citation

Jasperson, Kory W.. "Genetic Testing By Cancer Site: Colon (polyposis Syndromes)." Cancer Journal (Sudbury, Mass.), vol. 18, no. 4, 2012, pp. 328-33.
Jasperson KW. Genetic testing by cancer site: colon (polyposis syndromes). Cancer J. 2012;18(4):328-33.
Jasperson, K. W. (2012). Genetic testing by cancer site: colon (polyposis syndromes). Cancer Journal (Sudbury, Mass.), 18(4), 328-33. https://doi.org/10.1097/PPO.0b013e3182609300
Jasperson KW. Genetic Testing By Cancer Site: Colon (polyposis Syndromes). Cancer J. 2012 Jul-Aug;18(4):328-33. PubMed PMID: 22846733.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Genetic testing by cancer site: colon (polyposis syndromes). A1 - Jasperson,Kory W, PY - 2012/8/1/entrez PY - 2012/8/1/pubmed PY - 2013/1/31/medline SP - 328 EP - 33 JF - Cancer journal (Sudbury, Mass.) JO - Cancer J VL - 18 IS - 4 N2 - Hereditary colonic polyposis conditions are all characterized by high rates of cancer, but they have diverse phenotypes, genetic heterogeneity, and assorted inheritance patterns. The most well known of these conditions include familial adenomatous polyposis, attenuated familial adenomatous polyposis, MUTYH (MutY human homolog)-associated polyposis, Peutz-Jeghers syndrome, juvenile polyposis syndrome, and Cowden syndrome. Early recognition of these conditions is not only vital for management in affected individuals, but also for prevention and early detection in at-risk relatives. Reviewed here are the genetic testing strategies for colonic polyposis, as well as an overview of characteristic features and management considerations for these syndromes. SN - 1540-336X UR - https://www.unboundmedicine.com/medline/citation/22846733/Genetic_testing_by_cancer_site:_colon__polyposis_syndromes__ L2 - http://dx.doi.org/10.1097/PPO.0b013e3182609300 DB - PRIME DP - Unbound Medicine ER -