Tags

Type your tag names separated by a space and hit enter

Towards hemostatic resuscitation: the changing understanding of acute traumatic biology, massive bleeding, and damage-control resuscitation.
Surg Clin North Am. 2012 Aug; 92(4):877-91, viii.SC

Abstract

During the past decade there has been a profound change in the understanding of postinjury coagulation. Concurrently, new data suggest that a resuscitative strategy to minimize large volumes of crystalloid while recreating whole is associated with reduced morbidity and mortality. This article outlines the history of resuscitation and transfusion practices in trauma, the changing understanding of coagulation and inflammation, and clinical data driving changes in resuscitative conduct. Finally, the current state of the science suggests future basic science and clinical investigation that will drive changes in transfusion and resuscitation in severely injured military personnel and civilian patients.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Cohen MJ
Department of Surgery, San Francisco General Hospital and the University of California, San Francisco, 1001 Potrero Avenue, Ward 3A, San Francisco, CA 94110, USA. mcohen@sfghsurg.ucsf.edu

MeSH

Blood Coagulation DisordersBlood TransfusionFluid TherapyHemostatic TechniquesHistory, 20th CenturyHistory, 21st CenturyHumansMilitary MedicineResuscitationShock, HemorrhagicTransfusion ReactionTraumatologyUnited StatesWounds and Injuries

Pub Type(s)

Historical Article
Journal Article
Review

Language

eng

PubMed ID

22850152

Citation

Cohen, Mitchell Jay. "Towards Hemostatic Resuscitation: the Changing Understanding of Acute Traumatic Biology, Massive Bleeding, and Damage-control Resuscitation." The Surgical Clinics of North America, vol. 92, no. 4, 2012, pp. 877-91, viii.
Cohen MJ. Towards hemostatic resuscitation: the changing understanding of acute traumatic biology, massive bleeding, and damage-control resuscitation. Surg Clin North Am. 2012;92(4):877-91, viii.
Cohen, M. J. (2012). Towards hemostatic resuscitation: the changing understanding of acute traumatic biology, massive bleeding, and damage-control resuscitation. The Surgical Clinics of North America, 92(4), 877-91, viii. https://doi.org/10.1016/j.suc.2012.06.001
Cohen MJ. Towards Hemostatic Resuscitation: the Changing Understanding of Acute Traumatic Biology, Massive Bleeding, and Damage-control Resuscitation. Surg Clin North Am. 2012;92(4):877-91, viii. PubMed PMID: 22850152.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Towards hemostatic resuscitation: the changing understanding of acute traumatic biology, massive bleeding, and damage-control resuscitation. A1 - Cohen,Mitchell Jay, PY - 2012/8/2/entrez PY - 2012/8/2/pubmed PY - 2012/10/10/medline SP - 877-91, viii JF - The Surgical clinics of North America JO - Surg Clin North Am VL - 92 IS - 4 N2 - During the past decade there has been a profound change in the understanding of postinjury coagulation. Concurrently, new data suggest that a resuscitative strategy to minimize large volumes of crystalloid while recreating whole is associated with reduced morbidity and mortality. This article outlines the history of resuscitation and transfusion practices in trauma, the changing understanding of coagulation and inflammation, and clinical data driving changes in resuscitative conduct. Finally, the current state of the science suggests future basic science and clinical investigation that will drive changes in transfusion and resuscitation in severely injured military personnel and civilian patients. SN - 1558-3171 UR - https://www.unboundmedicine.com/medline/citation/22850152/Towards_hemostatic_resuscitation:_the_changing_understanding_of_acute_traumatic_biology_massive_bleeding_and_damage_control_resuscitation_ DB - PRIME DP - Unbound Medicine ER -