Tags

Type your tag names separated by a space and hit enter

Therapeutic penetrating keratoplasty in severe infective keratitis using glycerol-preserved donor corneas.
Cornea 2012; 31(10):1103-6C

Abstract

PURPOSE

To report the surgical outcome of therapeutic penetrating keratoplasty (TPKP) using glycerol-preserved donor corneas in severe infective keratitis.

METHODS

Glycerol-preserved corneas were obtained from the recipient corneas of the patients who underwent optical penetrating keratoplasty and preserved in glycerol. Eight eyes of 8 patients (3 men/5 women; average age, 69.7 years) with severe corneal ulcer with perforation were treated with TPKP using glycerol-preserved corneas.

RESULTS

With a mean follow-up time of 31.1 months (range, 9-58 months), satisfactory anatomical integrity was obtained in 7 patients (87.5%) at the end of the follow-up. Eradication of infection without recurrence was obtained in 7 eyes (87.5%). The mean reepithelialization time was 10.2 days. One patient (12.5%) received secondary optical penetrating keratoplasty. The pre-TPKP visual acuity ranged from no light perception to 0.06. After surgery, 4 eyes (50%) improved or maintained preoperative visual acuity and four eyes (50%) had no light perception but maintained anatomical integrity. One had a recurrent infection and needed antibiotics and amniotic membrane graft. One suffered from secondary glaucoma and received evisceration 19 months later.

CONCLUSIONS

Glycerol-preserved donor corneas may be effective substitutes in TPKP to control severe infective keratitis and preserve anatomical integrity.

Authors+Show Affiliations

Department of Ophthalmology, Chang Gung Memorial Hospital at Keelung, Chang Gung University College of Medicine, Taoyuan, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22854559

Citation

Yang, Ju-Wen, et al. "Therapeutic Penetrating Keratoplasty in Severe Infective Keratitis Using Glycerol-preserved Donor Corneas." Cornea, vol. 31, no. 10, 2012, pp. 1103-6.
Yang JW, Lin HC, Hsiao CH, et al. Therapeutic penetrating keratoplasty in severe infective keratitis using glycerol-preserved donor corneas. Cornea. 2012;31(10):1103-6.
Yang, J. W., Lin, H. C., Hsiao, C. H., & Chen, P. Y. (2012). Therapeutic penetrating keratoplasty in severe infective keratitis using glycerol-preserved donor corneas. Cornea, 31(10), pp. 1103-6. doi:10.1097/ICO.0b013e31821c9ba2.
Yang JW, et al. Therapeutic Penetrating Keratoplasty in Severe Infective Keratitis Using Glycerol-preserved Donor Corneas. Cornea. 2012;31(10):1103-6. PubMed PMID: 22854559.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Therapeutic penetrating keratoplasty in severe infective keratitis using glycerol-preserved donor corneas. AU - Yang,Ju-Wen, AU - Lin,Hsin-Chiung, AU - Hsiao,Ching-Hsi, AU - Chen,Phil Y F, PY - 2012/8/3/entrez PY - 2012/8/3/pubmed PY - 2012/12/13/medline SP - 1103 EP - 6 JF - Cornea JO - Cornea VL - 31 IS - 10 N2 - PURPOSE: To report the surgical outcome of therapeutic penetrating keratoplasty (TPKP) using glycerol-preserved donor corneas in severe infective keratitis. METHODS: Glycerol-preserved corneas were obtained from the recipient corneas of the patients who underwent optical penetrating keratoplasty and preserved in glycerol. Eight eyes of 8 patients (3 men/5 women; average age, 69.7 years) with severe corneal ulcer with perforation were treated with TPKP using glycerol-preserved corneas. RESULTS: With a mean follow-up time of 31.1 months (range, 9-58 months), satisfactory anatomical integrity was obtained in 7 patients (87.5%) at the end of the follow-up. Eradication of infection without recurrence was obtained in 7 eyes (87.5%). The mean reepithelialization time was 10.2 days. One patient (12.5%) received secondary optical penetrating keratoplasty. The pre-TPKP visual acuity ranged from no light perception to 0.06. After surgery, 4 eyes (50%) improved or maintained preoperative visual acuity and four eyes (50%) had no light perception but maintained anatomical integrity. One had a recurrent infection and needed antibiotics and amniotic membrane graft. One suffered from secondary glaucoma and received evisceration 19 months later. CONCLUSIONS: Glycerol-preserved donor corneas may be effective substitutes in TPKP to control severe infective keratitis and preserve anatomical integrity. SN - 1536-4798 UR - https://www.unboundmedicine.com/medline/citation/22854559/Therapeutic_penetrating_keratoplasty_in_severe_infective_keratitis_using_glycerol_preserved_donor_corneas_ L2 - http://Insights.ovid.com/pubmed?pmid=22854559 DB - PRIME DP - Unbound Medicine ER -