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Seasonal trends of microbial keratitis in South India.
Cornea 2012; 31(10):1123-7C

Abstract

PURPOSE

Previous studies suggest that fungal keratitis is more common in hot humid climates and that bacterial keratitis is independent of seasonal variation. This study analyzes seasonal trends in the incidence of fungal and bacterial keratitis at the Aravind Eye Hospital in southeast India.

METHODS

Using microbiology records from August 2006 to July 2009, retrospective analyses of infectious keratitis were performed. Bacterial and fungal keratitis incidence data were analyzed for seasonal patterns.

RESULTS

Among the 6967 infectious keratitis cases, cultures were performed in 5221 (74.9%) cases; among them, 3028 (58%) were positive. Of the culture-positive cases, 1908 (63%) and 1081 (35.7%) were of fungal and bacterial etiology, respectively. The predominant fungal organism was Fusarium spp (42.3%) and the predominant bacterial organisms were Streptococcus pneumoniae (35.1%), Pseudomonas aeruginosa (24.3%), and Nocardia spp (8.1%). Analyses revealed an uneven distribution of fungal keratitis throughout the year (P < 0.001) with peaks in July and January. No significant seasonal trend was observed for the combined bacterial keratitis group.

CONCLUSIONS

A higher incidence of fungal keratitis occurs during the months corresponding to the windy and harvest seasons, during which time infection from vegetative corneal injury may be more likely. Robust screening efforts during these periods may mitigate visually debilitating sequelae from infectious keratitis.

Authors+Show Affiliations

Department of Ophthalmology, University of California San Francisco, San Francisco, CA 94143-0412, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22868629

Citation

Lin, Charles C., et al. "Seasonal Trends of Microbial Keratitis in South India." Cornea, vol. 31, no. 10, 2012, pp. 1123-7.
Lin CC, Lalitha P, Srinivasan M, et al. Seasonal trends of microbial keratitis in South India. Cornea. 2012;31(10):1123-7.
Lin, C. C., Lalitha, P., Srinivasan, M., Prajna, N. V., McLeod, S. D., Acharya, N. R., ... Porco, T. C. (2012). Seasonal trends of microbial keratitis in South India. Cornea, 31(10), pp. 1123-7. doi:10.1097/ICO.0b013e31825694d3.
Lin CC, et al. Seasonal Trends of Microbial Keratitis in South India. Cornea. 2012;31(10):1123-7. PubMed PMID: 22868629.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seasonal trends of microbial keratitis in South India. AU - Lin,Charles C, AU - Lalitha,Prajna, AU - Srinivasan,Muthiah, AU - Prajna,N Venkatesh, AU - McLeod,Stephen D, AU - Acharya,Nisha R, AU - Lietman,Thomas M, AU - Porco,Travis C, PY - 2012/8/8/entrez PY - 2012/8/8/pubmed PY - 2012/12/13/medline SP - 1123 EP - 7 JF - Cornea JO - Cornea VL - 31 IS - 10 N2 - PURPOSE: Previous studies suggest that fungal keratitis is more common in hot humid climates and that bacterial keratitis is independent of seasonal variation. This study analyzes seasonal trends in the incidence of fungal and bacterial keratitis at the Aravind Eye Hospital in southeast India. METHODS: Using microbiology records from August 2006 to July 2009, retrospective analyses of infectious keratitis were performed. Bacterial and fungal keratitis incidence data were analyzed for seasonal patterns. RESULTS: Among the 6967 infectious keratitis cases, cultures were performed in 5221 (74.9%) cases; among them, 3028 (58%) were positive. Of the culture-positive cases, 1908 (63%) and 1081 (35.7%) were of fungal and bacterial etiology, respectively. The predominant fungal organism was Fusarium spp (42.3%) and the predominant bacterial organisms were Streptococcus pneumoniae (35.1%), Pseudomonas aeruginosa (24.3%), and Nocardia spp (8.1%). Analyses revealed an uneven distribution of fungal keratitis throughout the year (P < 0.001) with peaks in July and January. No significant seasonal trend was observed for the combined bacterial keratitis group. CONCLUSIONS: A higher incidence of fungal keratitis occurs during the months corresponding to the windy and harvest seasons, during which time infection from vegetative corneal injury may be more likely. Robust screening efforts during these periods may mitigate visually debilitating sequelae from infectious keratitis. SN - 1536-4798 UR - https://www.unboundmedicine.com/medline/citation/22868629/Seasonal_trends_of_microbial_keratitis_in_South_India_ L2 - http://Insights.ovid.com/pubmed?pmid=22868629 DB - PRIME DP - Unbound Medicine ER -