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Determination of 10 ginsenosides in Panax ginseng of different harvest times based on HPLC fingerprints and principal component analysis.
Nat Prod Res. 2013; 27(9):851-4.NP

Abstract

A combinative method of HPLC fingerprinting and quantitative determination was successfully applied to monitor dynamic accumulation of ginsenosides in five-year-old Panax ginseng roots from different harvest times. The optimal chromatographic conditions were achieved on a C18 column with gradient elution using acetonitrile and 1 mmol · L(-1) KH2PO4 buffer solution at 203 nm. The result indicated that the contents of total ginsenosides showed significant variations, and a decrease tendency appeared in the growth period of the fifth year.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Chen F
State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, People's Republic of China.
Luo J
No affiliation info available
Kong L
No affiliation info available

MeSH

AcetonitrilesChromatography, High Pressure LiquidGinsenosidesPanaxPlant RootsPrincipal Component AnalysisReproducibility of Results

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22871218

Citation

Chen, Fengqin, et al. "Determination of 10 Ginsenosides in Panax Ginseng of Different Harvest Times Based On HPLC Fingerprints and Principal Component Analysis." Natural Product Research, vol. 27, no. 9, 2013, pp. 851-4.
Chen F, Luo J, Kong L. Determination of 10 ginsenosides in Panax ginseng of different harvest times based on HPLC fingerprints and principal component analysis. Nat Prod Res. 2013;27(9):851-4.
Chen, F., Luo, J., & Kong, L. (2013). Determination of 10 ginsenosides in Panax ginseng of different harvest times based on HPLC fingerprints and principal component analysis. Natural Product Research, 27(9), 851-4. https://doi.org/10.1080/14786419.2012.711758
Chen F, Luo J, Kong L. Determination of 10 Ginsenosides in Panax Ginseng of Different Harvest Times Based On HPLC Fingerprints and Principal Component Analysis. Nat Prod Res. 2013;27(9):851-4. PubMed PMID: 22871218.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Determination of 10 ginsenosides in Panax ginseng of different harvest times based on HPLC fingerprints and principal component analysis. AU - Chen,Fengqin, AU - Luo,Jianguang, AU - Kong,Lingyi, Y1 - 2012/08/07/ PY - 2012/8/9/entrez PY - 2012/8/9/pubmed PY - 2014/1/16/medline SP - 851 EP - 4 JF - Natural product research JO - Nat Prod Res VL - 27 IS - 9 N2 - A combinative method of HPLC fingerprinting and quantitative determination was successfully applied to monitor dynamic accumulation of ginsenosides in five-year-old Panax ginseng roots from different harvest times. The optimal chromatographic conditions were achieved on a C18 column with gradient elution using acetonitrile and 1 mmol · L(-1) KH2PO4 buffer solution at 203 nm. The result indicated that the contents of total ginsenosides showed significant variations, and a decrease tendency appeared in the growth period of the fifth year. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/22871218/Determination_of_10_ginsenosides_in_Panax_ginseng_of_different_harvest_times_based_on_HPLC_fingerprints_and_principal_component_analysis_ DB - PRIME DP - Unbound Medicine ER -