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Vitamin D status in children with Hashimoto thyroiditis.
J Pediatr Endocrinol Metab. 2012; 25(5-6):467-70.JP

Abstract

OBJECTIVE

To investigate vitamin D status in children with Hashimoto thyroiditis.

SUBJECTS AND METHODS

The study group consisted of 78 children recently diagnosed as Hashimoto thyroiditis and 74 subjects as the control group. Parameters of calcium metabolism, thyroid function tests, and 25-hydroxyvitamin D [25(OH)D] levels were measured.

RESULTS

Vitamin D deficiency rate was significantly higher in the Hashimoto group compared with the control subjects (73.1% vs. 17.6%, p < 0.0001). In the Hashimoto group, mean 25(OH)D levels were significantly lower compared with the control group (31.2 +/- 11.5 versus 57.9 +/- 19.7 nmol/L, p < 0.001) and was inversely correlated with the anti-thyroid peroxidase (anti-TPO) levels (r = -0.30, p = 0.007).

CONCLUSION

The higher vitamin D deficiency rates besides lower vitamin D levels in the Hashimoto group together with the inverse correlation between vitamin D and anti-TPO suggest that vitamin D deficiency may have a role in the autoimmune process in Hashimoto thyroiditis in children.

Authors+Show Affiliations

Department of Pediatric Endocrinology, School of Medicine, Gazi University, Ankara, Turkey. turkalpo@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22876540

Citation

Camurdan, Orhun M., et al. "Vitamin D Status in Children With Hashimoto Thyroiditis." Journal of Pediatric Endocrinology & Metabolism : JPEM, vol. 25, no. 5-6, 2012, pp. 467-70.
Camurdan OM, Döğer E, Bideci A, et al. Vitamin D status in children with Hashimoto thyroiditis. J Pediatr Endocrinol Metab. 2012;25(5-6):467-70.
Camurdan, O. M., Döğer, E., Bideci, A., Celik, N., & Cinaz, P. (2012). Vitamin D status in children with Hashimoto thyroiditis. Journal of Pediatric Endocrinology & Metabolism : JPEM, 25(5-6), 467-70.
Camurdan OM, et al. Vitamin D Status in Children With Hashimoto Thyroiditis. J Pediatr Endocrinol Metab. 2012;25(5-6):467-70. PubMed PMID: 22876540.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vitamin D status in children with Hashimoto thyroiditis. AU - Camurdan,Orhun M, AU - Döğer,Esra, AU - Bideci,Aysun, AU - Celik,Nurullah, AU - Cinaz,Peyami, PY - 2012/8/11/entrez PY - 2012/8/11/pubmed PY - 2012/9/5/medline SP - 467 EP - 70 JF - Journal of pediatric endocrinology & metabolism : JPEM JO - J. Pediatr. Endocrinol. Metab. VL - 25 IS - 5-6 N2 - OBJECTIVE: To investigate vitamin D status in children with Hashimoto thyroiditis. SUBJECTS AND METHODS: The study group consisted of 78 children recently diagnosed as Hashimoto thyroiditis and 74 subjects as the control group. Parameters of calcium metabolism, thyroid function tests, and 25-hydroxyvitamin D [25(OH)D] levels were measured. RESULTS: Vitamin D deficiency rate was significantly higher in the Hashimoto group compared with the control subjects (73.1% vs. 17.6%, p < 0.0001). In the Hashimoto group, mean 25(OH)D levels were significantly lower compared with the control group (31.2 +/- 11.5 versus 57.9 +/- 19.7 nmol/L, p < 0.001) and was inversely correlated with the anti-thyroid peroxidase (anti-TPO) levels (r = -0.30, p = 0.007). CONCLUSION: The higher vitamin D deficiency rates besides lower vitamin D levels in the Hashimoto group together with the inverse correlation between vitamin D and anti-TPO suggest that vitamin D deficiency may have a role in the autoimmune process in Hashimoto thyroiditis in children. SN - 0334-018X UR - https://www.unboundmedicine.com/medline/citation/22876540/Vitamin_D_status_in_children_with_Hashimoto_thyroiditis_ L2 - http://www.diseaseinfosearch.org/result/3247 DB - PRIME DP - Unbound Medicine ER -