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A life-threatening flecainide overdose treated with intravenous fat emulsion.
Pacing Clin Electrophysiol. 2013 Mar; 36(3):e87-9.PC

Abstract

Flecainide is a Vaughan Williams Class Ic antidysrhythmic associated with PR, QRS, and QTc prolongation on the electrocardiogram and development of life-threatening cardiac toxicity in overdose. The cornerstone of treatment is fluid resuscitation and the administration of magnesium and sodium bicarbonate. We report a case of flecainide overdose associated with life-threatening hemodynamic compromise successfully treated with intravenous fat emulsion (IFE) therapy. IFE should be considered as a novel adjunctive therapy in patients with life-threatening toxicity following flecainide overdose.

Authors+Show Affiliations

Department of Emergency Medicine, Regions Hospital, St. Paul, MN 55101, USA. heatherellsworth9@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22882363

Citation

Ellsworth, Heather, et al. "A Life-threatening Flecainide Overdose Treated With Intravenous Fat Emulsion." Pacing and Clinical Electrophysiology : PACE, vol. 36, no. 3, 2013, pp. e87-9.
Ellsworth H, Stellpflug SJ, Cole JB, et al. A life-threatening flecainide overdose treated with intravenous fat emulsion. Pacing Clin Electrophysiol. 2013;36(3):e87-9.
Ellsworth, H., Stellpflug, S. J., Cole, J. B., Dolan, J. A., & Harris, C. R. (2013). A life-threatening flecainide overdose treated with intravenous fat emulsion. Pacing and Clinical Electrophysiology : PACE, 36(3), e87-9. https://doi.org/10.1111/j.1540-8159.2012.03485.x
Ellsworth H, et al. A Life-threatening Flecainide Overdose Treated With Intravenous Fat Emulsion. Pacing Clin Electrophysiol. 2013;36(3):e87-9. PubMed PMID: 22882363.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A life-threatening flecainide overdose treated with intravenous fat emulsion. AU - Ellsworth,Heather, AU - Stellpflug,Samuel J, AU - Cole,Jon B, AU - Dolan,Joseph A, AU - Harris,Carson R, Y1 - 2012/08/08/ PY - 2011/07/23/received PY - 2012/04/02/revised PY - 2012/04/25/accepted PY - 2012/8/14/entrez PY - 2012/8/14/pubmed PY - 2013/9/14/medline SP - e87 EP - 9 JF - Pacing and clinical electrophysiology : PACE JO - Pacing Clin Electrophysiol VL - 36 IS - 3 N2 - Flecainide is a Vaughan Williams Class Ic antidysrhythmic associated with PR, QRS, and QTc prolongation on the electrocardiogram and development of life-threatening cardiac toxicity in overdose. The cornerstone of treatment is fluid resuscitation and the administration of magnesium and sodium bicarbonate. We report a case of flecainide overdose associated with life-threatening hemodynamic compromise successfully treated with intravenous fat emulsion (IFE) therapy. IFE should be considered as a novel adjunctive therapy in patients with life-threatening toxicity following flecainide overdose. SN - 1540-8159 UR - https://www.unboundmedicine.com/medline/citation/22882363/A_life_threatening_flecainide_overdose_treated_with_intravenous_fat_emulsion_ L2 - https://doi.org/10.1111/j.1540-8159.2012.03485.x DB - PRIME DP - Unbound Medicine ER -