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Effect of the 532nm pulsed KTP laser in the treatment of Reinke's edema.
Laryngoscope. 2012 Dec; 122(12):2786-92.L

Abstract

OBJECTIVES/HYPOTHESIS

To evaluate the effect and safety of the 532nm Pulsed Potassium-Titanyl-Phosphate (KTP) laser in the office-based treatment of patients with Reinke's edema using objective and subjective scaled outcome measures.

STUDY DESIGN

Case Series.

SETTING

Tertiary hospital center.

SUBJECTS

Seven adult females undergoing in-office KTP laser treatment for Reinke's edema.

METHODS

Participants were studied pre- and posttreatment. Vocal function was evaluated by objective aerodynamic and acoustic analysis. Subjective changes were evaluated using the GRBAS scale, Voice Handicap Index, and videostroboscopy. Histologic effects of the laser were investigated by comparing one patient treated with laser one year prior to excision, one treated with laser just prior to excision, and one control patient who underwent excision without prior laser treatment.

RESULTS

At an average postoperative follow up of 17.8 weeks (range 5-78), maximum phonation time trended toward improvement. The median VHI score decreased from 37 to 26 (p=0.150). There was a reduction in each component of the GRBAS scoring and the median fundamental frequency increased from 162 to 186 (p=0.625). Stroboscopic findings demonstrated an intact posttreatment mucosal wave. Histologic comparison of the tissue effects of laser in three patients demonstrated changes in vocal fold vascularity but no acute or long-term damage to the overlying epithelium.

CONCLUSION

Objective and subjective scaled measures suggest that treatment of Reinke's edema in the office with a 532nm KTP laser may result in improved voice. It appears safe with histologic preservation of the vocal fold vibratory epithelium and persistence of mucosal wave.

Authors+Show Affiliations

Department of Otolaryngology, the Voice and Swallowing Institute, New York Eye & Ear Infirmary, New York, New York 10003, USA. mpitman@nyee.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

22886907

Citation

Pitman, Michael J., et al. "Effect of the 532nm Pulsed KTP Laser in the Treatment of Reinke's Edema." The Laryngoscope, vol. 122, no. 12, 2012, pp. 2786-92.
Pitman MJ, Lebowitz-Cooper A, Iacob C, et al. Effect of the 532nm pulsed KTP laser in the treatment of Reinke's edema. Laryngoscope. 2012;122(12):2786-92.
Pitman, M. J., Lebowitz-Cooper, A., Iacob, C., & Tan, M. (2012). Effect of the 532nm pulsed KTP laser in the treatment of Reinke's edema. The Laryngoscope, 122(12), 2786-92. https://doi.org/10.1002/lary.23576
Pitman MJ, et al. Effect of the 532nm Pulsed KTP Laser in the Treatment of Reinke's Edema. Laryngoscope. 2012;122(12):2786-92. PubMed PMID: 22886907.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of the 532nm pulsed KTP laser in the treatment of Reinke's edema. AU - Pitman,Michael J, AU - Lebowitz-Cooper,Amy, AU - Iacob,Chodrin, AU - Tan,Meilin, Y1 - 2012/08/08/ PY - 2012/06/18/accepted PY - 2012/8/14/entrez PY - 2012/8/14/pubmed PY - 2013/2/13/medline SP - 2786 EP - 92 JF - The Laryngoscope JO - Laryngoscope VL - 122 IS - 12 N2 - OBJECTIVES/HYPOTHESIS: To evaluate the effect and safety of the 532nm Pulsed Potassium-Titanyl-Phosphate (KTP) laser in the office-based treatment of patients with Reinke's edema using objective and subjective scaled outcome measures. STUDY DESIGN: Case Series. SETTING: Tertiary hospital center. SUBJECTS: Seven adult females undergoing in-office KTP laser treatment for Reinke's edema. METHODS: Participants were studied pre- and posttreatment. Vocal function was evaluated by objective aerodynamic and acoustic analysis. Subjective changes were evaluated using the GRBAS scale, Voice Handicap Index, and videostroboscopy. Histologic effects of the laser were investigated by comparing one patient treated with laser one year prior to excision, one treated with laser just prior to excision, and one control patient who underwent excision without prior laser treatment. RESULTS: At an average postoperative follow up of 17.8 weeks (range 5-78), maximum phonation time trended toward improvement. The median VHI score decreased from 37 to 26 (p=0.150). There was a reduction in each component of the GRBAS scoring and the median fundamental frequency increased from 162 to 186 (p=0.625). Stroboscopic findings demonstrated an intact posttreatment mucosal wave. Histologic comparison of the tissue effects of laser in three patients demonstrated changes in vocal fold vascularity but no acute or long-term damage to the overlying epithelium. CONCLUSION: Objective and subjective scaled measures suggest that treatment of Reinke's edema in the office with a 532nm KTP laser may result in improved voice. It appears safe with histologic preservation of the vocal fold vibratory epithelium and persistence of mucosal wave. SN - 1531-4995 UR - https://www.unboundmedicine.com/medline/citation/22886907/Effect_of_the_532nm_pulsed_KTP_laser_in_the_treatment_of_Reinke's_edema_ L2 - https://doi.org/10.1002/lary.23576 DB - PRIME DP - Unbound Medicine ER -