Abstract
While there is no cure for autism spectrum disorder, psychopharmacologic agents are often used with behavioral and educational approaches to treat its comorbid symptoms of hyperactivity, irritability, and aggression. Studies suggest that at least 50% of persons with autism spectrum disorder receive psychotropic medications during their life span. This selective review examines recent studies about the use of psychotropic medications in persons with autism spectrum disorder. The aim was to focus on randomized controlled trials conducted from 1990 to 2010 on this topic. A comprehensive literature search was performed using PubMed and Cochrane databases. Out of 105 studies identified for the review, only 24 were randomized controlled trials. Thus, despite the common use of these medications in autism spectrum disorder, more controlled studies are needed to determine their long-term efficacy and safety.
TY - JOUR
T1 - Psychopharmacology of autism spectrum disorders: a selective review.
AU - Mohiuddin,Sarah,
AU - Ghaziuddin,Mohammad,
Y1 - 2012/08/14/
PY - 2012/8/16/entrez
PY - 2012/8/16/pubmed
PY - 2014/6/17/medline
KW - autism
KW - comorbidity
KW - psychopharmacology
SP - 645
EP - 54
JF - Autism : the international journal of research and practice
JO - Autism
VL - 17
IS - 6
N2 - While there is no cure for autism spectrum disorder, psychopharmacologic agents are often used with behavioral and educational approaches to treat its comorbid symptoms of hyperactivity, irritability, and aggression. Studies suggest that at least 50% of persons with autism spectrum disorder receive psychotropic medications during their life span. This selective review examines recent studies about the use of psychotropic medications in persons with autism spectrum disorder. The aim was to focus on randomized controlled trials conducted from 1990 to 2010 on this topic. A comprehensive literature search was performed using PubMed and Cochrane databases. Out of 105 studies identified for the review, only 24 were randomized controlled trials. Thus, despite the common use of these medications in autism spectrum disorder, more controlled studies are needed to determine their long-term efficacy and safety.
SN - 1461-7005
UR - https://www.unboundmedicine.com/medline/citation/22892891/Psychopharmacology_of_autism_spectrum_disorders:_a_selective_review_
L2 - https://journals.sagepub.com/doi/10.1177/1362361312453776?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed
DB - PRIME
DP - Unbound Medicine
ER -