Tags

Type your tag names separated by a space and hit enter

Cerebral and spinal schistosomiasis.
Curr Neurol Neurosci Rep. 2012 Dec; 12(6):666-74.CN

Abstract

Cerebral schistosomiasis and spinal schistosomiasis are severe underrecognized complications of Schistosoma sp. infection, and can occur at any time during the parasitic infection. Neuroschistosomiasis has been increasingly reported not only in endemic areas but also in Western countries owing to immigration and international travel. Immunogenic interaction between schistosome egg deposition and the delayed hypersensitivity reaction of the host are the main neuropathogenic mechanisms involved. Eggs induce a periovular granulomatous reaction in the tissues. In some cases, schistosome adult worms may aberrantly migrate to the central nervous system via the vertebral venous plexus and place the ova at an ectopic site. Headache and seizures are common in cerebral schistosomiasis, and intracranial hypertension and hydrocephalus may occur in tumour-like and cerebellar schistosomiasis. Spinal schistosomiasis may manifest itself as acute myelitis and/or myeloradiculopathy. Recognition of neuroschistosomiasis is important so that early treatment with praziquantel and steroids can be started in an attempt to prevent severe disability.

Authors+Show Affiliations

Medicine and Health Sciences Faculty, Universitat Internacional de Catalunya, Barcelona, Spain. fjcarod-artal@hotmail.com

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22903225

Citation

Carod Artal, Francisco Javier. "Cerebral and Spinal Schistosomiasis." Current Neurology and Neuroscience Reports, vol. 12, no. 6, 2012, pp. 666-74.
Carod Artal FJ. Cerebral and spinal schistosomiasis. Curr Neurol Neurosci Rep. 2012;12(6):666-74.
Carod Artal, F. J. (2012). Cerebral and spinal schistosomiasis. Current Neurology and Neuroscience Reports, 12(6), 666-74. https://doi.org/10.1007/s11910-012-0305-4
Carod Artal FJ. Cerebral and Spinal Schistosomiasis. Curr Neurol Neurosci Rep. 2012;12(6):666-74. PubMed PMID: 22903225.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cerebral and spinal schistosomiasis. A1 - Carod Artal,Francisco Javier, PY - 2012/8/21/entrez PY - 2012/8/21/pubmed PY - 2013/4/13/medline SP - 666 EP - 74 JF - Current neurology and neuroscience reports JO - Curr Neurol Neurosci Rep VL - 12 IS - 6 N2 - Cerebral schistosomiasis and spinal schistosomiasis are severe underrecognized complications of Schistosoma sp. infection, and can occur at any time during the parasitic infection. Neuroschistosomiasis has been increasingly reported not only in endemic areas but also in Western countries owing to immigration and international travel. Immunogenic interaction between schistosome egg deposition and the delayed hypersensitivity reaction of the host are the main neuropathogenic mechanisms involved. Eggs induce a periovular granulomatous reaction in the tissues. In some cases, schistosome adult worms may aberrantly migrate to the central nervous system via the vertebral venous plexus and place the ova at an ectopic site. Headache and seizures are common in cerebral schistosomiasis, and intracranial hypertension and hydrocephalus may occur in tumour-like and cerebellar schistosomiasis. Spinal schistosomiasis may manifest itself as acute myelitis and/or myeloradiculopathy. Recognition of neuroschistosomiasis is important so that early treatment with praziquantel and steroids can be started in an attempt to prevent severe disability. SN - 1534-6293 UR - https://www.unboundmedicine.com/medline/citation/22903225/Cerebral_and_spinal_schistosomiasis_ L2 - https://dx.doi.org/10.1007/s11910-012-0305-4 DB - PRIME DP - Unbound Medicine ER -