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[Zinc-protoporphyrin determination in patients with sideropenic anemia and insufficient erythropoiesis].
Recenti Prog Med. 1990 Oct; 81(10):658-60.RP

Abstract

We have measured erythrocyte Zinc-Protoporphyrin and serum ferritin in 125 subjects: 100 seemingly healthy controls, 17 with sideropenic anemia and 8 with erythropoietic insufficiency (sideropenia without anemia). Erythrocyte Zinc-Protoporphyrin was measured using Protofluor Z (Helena--Lab.) and serum ferritin was tested with immunoenzymatic technics. Patients with sideropenic anemia showed erythrocyte Zinc-Protoporphyrin values higher than controls, whereas serum ferritin was significantly lower than controls. Patients with erythropoietic insufficiency also showed erythrocyte Zinc-Protoporphyrin values higher than controls with statistical significance whereas the decrease of serum ferritin was not significant. Our study showed that Zinc-Protoporphyrin, in conjunction with serum ferritin, is a very useful test for evaluation of iron storage.

Authors+Show Affiliations

D'Angelo G
Laboratorio di Analisi chimico-cliniche, Ematologia e Microbiologia, Presidio ospedaliero di Somma Lombardo, U.S.S.L. n. 6, Gallarate.
Giardini C
No affiliation info available
Zanco MD
No affiliation info available

MeSH

AdultAnemia, HypochromicDiagnosis, DifferentialErythropoiesisFerritinsHumansIron DeficienciesProtoporphyrinsZinc

Pub Type(s)

Comparative Study
Journal Article

Language

ita

PubMed ID

2291011

Citation

D'Angelo, G, et al. "[Zinc-protoporphyrin Determination in Patients With Sideropenic Anemia and Insufficient Erythropoiesis]." Recenti Progressi in Medicina, vol. 81, no. 10, 1990, pp. 658-60.
D'Angelo G, Giardini C, Zanco MD. [Zinc-protoporphyrin determination in patients with sideropenic anemia and insufficient erythropoiesis]. Recenti Prog Med. 1990;81(10):658-60.
D'Angelo, G., Giardini, C., & Zanco, M. D. (1990). [Zinc-protoporphyrin determination in patients with sideropenic anemia and insufficient erythropoiesis]. Recenti Progressi in Medicina, 81(10), 658-60.
D'Angelo G, Giardini C, Zanco MD. [Zinc-protoporphyrin Determination in Patients With Sideropenic Anemia and Insufficient Erythropoiesis]. Recenti Prog Med. 1990;81(10):658-60. PubMed PMID: 2291011.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Zinc-protoporphyrin determination in patients with sideropenic anemia and insufficient erythropoiesis]. AU - D'Angelo,G, AU - Giardini,C, AU - Zanco,M D, PY - 1990/10/1/pubmed PY - 1990/10/1/medline PY - 1990/10/1/entrez SP - 658 EP - 60 JF - Recenti progressi in medicina JO - Recenti Prog Med VL - 81 IS - 10 N2 - We have measured erythrocyte Zinc-Protoporphyrin and serum ferritin in 125 subjects: 100 seemingly healthy controls, 17 with sideropenic anemia and 8 with erythropoietic insufficiency (sideropenia without anemia). Erythrocyte Zinc-Protoporphyrin was measured using Protofluor Z (Helena--Lab.) and serum ferritin was tested with immunoenzymatic technics. Patients with sideropenic anemia showed erythrocyte Zinc-Protoporphyrin values higher than controls, whereas serum ferritin was significantly lower than controls. Patients with erythropoietic insufficiency also showed erythrocyte Zinc-Protoporphyrin values higher than controls with statistical significance whereas the decrease of serum ferritin was not significant. Our study showed that Zinc-Protoporphyrin, in conjunction with serum ferritin, is a very useful test for evaluation of iron storage. SN - 0034-1193 UR - https://www.unboundmedicine.com/medline/citation/2291011/[Zinc_protoporphyrin_determination_in_patients_with_sideropenic_anemia_and_insufficient_erythropoiesis]_ DB - PRIME DP - Unbound Medicine ER -