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Moisturizers: reality and the skin benefits.
Dermatol Ther. 2012 May-Jun; 25(3):229-33.DT

Abstract

The function of the skin as a barrier protects underlying tissues from infection, desiccation, chemicals, and mechanical stress. Disruption of this function results in increased transepidermal water loss or TEWL and is associated with conditions like atopic dermatitis and other chronic skin diseases. Moisturizers have been shown to improve these conditions through restoration of the integrity of the stratum corneum, acting as a barrier to water loss and replacement of skin lipids and other compounds. Also, moisturizers are commonly used to reduce fine lines and make skin appear smooth and soft. While many products make extensive claims of skin rejuvenation, many of the beneficial effects of these products are actually due to the moisturizers they contain: ingredients like glycerin, petrolatum, and dimethicone. Some newer formulations like prescription-device moisturizers, which received 510 K approval on the basis of reducing TEWL, are significantly more expensive than traditional moisturizers and recent literature does not indicate that they are more effective than their over-the-counter counterparts.

Authors+Show Affiliations

Department of Dermatology, Mount Sinai School of Medicine, New York, New York 10029, USA.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22913439

Citation

Nolan, Katherine, and Ellen Marmur. "Moisturizers: Reality and the Skin Benefits." Dermatologic Therapy, vol. 25, no. 3, 2012, pp. 229-33.
Nolan K, Marmur E. Moisturizers: reality and the skin benefits. Dermatol Ther. 2012;25(3):229-33.
Nolan, K., & Marmur, E. (2012). Moisturizers: reality and the skin benefits. Dermatologic Therapy, 25(3), 229-33. https://doi.org/10.1111/j.1529-8019.2012.01504.x
Nolan K, Marmur E. Moisturizers: Reality and the Skin Benefits. Dermatol Ther. 2012 May-Jun;25(3):229-33. PubMed PMID: 22913439.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Moisturizers: reality and the skin benefits. AU - Nolan,Katherine, AU - Marmur,Ellen, PY - 2012/8/24/entrez PY - 2012/8/24/pubmed PY - 2013/1/25/medline SP - 229 EP - 33 JF - Dermatologic therapy JO - Dermatol Ther VL - 25 IS - 3 N2 - The function of the skin as a barrier protects underlying tissues from infection, desiccation, chemicals, and mechanical stress. Disruption of this function results in increased transepidermal water loss or TEWL and is associated with conditions like atopic dermatitis and other chronic skin diseases. Moisturizers have been shown to improve these conditions through restoration of the integrity of the stratum corneum, acting as a barrier to water loss and replacement of skin lipids and other compounds. Also, moisturizers are commonly used to reduce fine lines and make skin appear smooth and soft. While many products make extensive claims of skin rejuvenation, many of the beneficial effects of these products are actually due to the moisturizers they contain: ingredients like glycerin, petrolatum, and dimethicone. Some newer formulations like prescription-device moisturizers, which received 510 K approval on the basis of reducing TEWL, are significantly more expensive than traditional moisturizers and recent literature does not indicate that they are more effective than their over-the-counter counterparts. SN - 1529-8019 UR - https://www.unboundmedicine.com/medline/citation/22913439/Moisturizers:_reality_and_the_skin_benefits_ L2 - https://doi.org/10.1111/j.1529-8019.2012.01504.x DB - PRIME DP - Unbound Medicine ER -