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Prenatal diagnosis of fetal cervicofacial anomalies.
Curr Opin Otolaryngol Head Neck Surg. 2012 Dec; 20(6):482-90.CO

Abstract

PURPOSE OF REVIEW

To review the current literature on prenatal diagnosis of cervicofacial anomalies that may require neonatal intervention or that require prenatal counseling by a maternal-fetal medicine team and otolaryngology, head and neck surgery.

RECENT FINDINGS

Ultrasound and MRI imaging are complementary in the prenatal diagnosis of fetal anomalies that may present with the need for the head and neck surgeon to assist with airway management at delivery or that require prenatal counseling. Team approaches to delivery of at-risk infants have improved and there is more experience with the ex-utero intrapartum treatment (EXIT) procedure. The importance of planning and simulation for EXIT is essential prior to delivery. Future directions include in-utero gene therapy and fetal surgery.

SUMMARY

Advances in detection and treatment of fetuses at risk for airway obstruction at birth and for accurate diagnosis of facial clefting will allow teams to continue to improve outcomes for these infants. Increased experience of such teams will allow refinement of protocols and indices for decision making regarding which fetuses will need treatment on placental support and which will do well with traditional delivery with treatment teams on standby. This will allow improved risk profiles for both mother and child.

Authors+Show Affiliations

Oregon Health and Science University, Portland, Oregon 97239, USA. macarthc@ohsu.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22913933

Citation

MacArthur, Carol J.. "Prenatal Diagnosis of Fetal Cervicofacial Anomalies." Current Opinion in Otolaryngology & Head and Neck Surgery, vol. 20, no. 6, 2012, pp. 482-90.
MacArthur CJ. Prenatal diagnosis of fetal cervicofacial anomalies. Curr Opin Otolaryngol Head Neck Surg. 2012;20(6):482-90.
MacArthur, C. J. (2012). Prenatal diagnosis of fetal cervicofacial anomalies. Current Opinion in Otolaryngology & Head and Neck Surgery, 20(6), 482-90. https://doi.org/10.1097/MOO.0b013e3283582e21
MacArthur CJ. Prenatal Diagnosis of Fetal Cervicofacial Anomalies. Curr Opin Otolaryngol Head Neck Surg. 2012;20(6):482-90. PubMed PMID: 22913933.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prenatal diagnosis of fetal cervicofacial anomalies. A1 - MacArthur,Carol J, PY - 2012/8/24/entrez PY - 2012/8/24/pubmed PY - 2013/5/17/medline SP - 482 EP - 90 JF - Current opinion in otolaryngology & head and neck surgery JO - Curr Opin Otolaryngol Head Neck Surg VL - 20 IS - 6 N2 - PURPOSE OF REVIEW: To review the current literature on prenatal diagnosis of cervicofacial anomalies that may require neonatal intervention or that require prenatal counseling by a maternal-fetal medicine team and otolaryngology, head and neck surgery. RECENT FINDINGS: Ultrasound and MRI imaging are complementary in the prenatal diagnosis of fetal anomalies that may present with the need for the head and neck surgeon to assist with airway management at delivery or that require prenatal counseling. Team approaches to delivery of at-risk infants have improved and there is more experience with the ex-utero intrapartum treatment (EXIT) procedure. The importance of planning and simulation for EXIT is essential prior to delivery. Future directions include in-utero gene therapy and fetal surgery. SUMMARY: Advances in detection and treatment of fetuses at risk for airway obstruction at birth and for accurate diagnosis of facial clefting will allow teams to continue to improve outcomes for these infants. Increased experience of such teams will allow refinement of protocols and indices for decision making regarding which fetuses will need treatment on placental support and which will do well with traditional delivery with treatment teams on standby. This will allow improved risk profiles for both mother and child. SN - 1531-6998 UR - https://www.unboundmedicine.com/medline/citation/22913933/Prenatal_diagnosis_of_fetal_cervicofacial_anomalies_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=22913933.ui DB - PRIME DP - Unbound Medicine ER -