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Radioactive iodine therapy.

Abstract

PURPOSE OF REVIEW

Review of the management decisions that must be made by the endocrinologist during the use of radioactive iodine (RAI) therapy of hyperthyroidism and differentiated thyroid cancer.

RECENT FINDINGS

Since the 1940s radioactive (131)I (RAI) therapy has been a major component of the treatment of hyperthyroidism and differentiated thyroid cancer. RAI is the most common definitive treatment of hyperthyroidism. Pretherapy decisions including use of antithyroid medication and low-iodine diet will be discussed with the relevant supportive literature. The method of semi-quantitative calculation used for RAI treatment of hyperthyroidism will be described. Evidence-based guideline for the management of differentiated thyroid cancer by the American Thyroid Association, new drug development and recent randomized controlled trials have changed current practice of how RAI is used for remnant ablation and adjuvant therapy of differentiated thyroid cancer.

SUMMARY

RAI is a common tool for the endocrinologist in the management of hyperthyroidism and differentiated thyroid cancer. Review of the management decisions and practice of RAI therapy will educate the endocrinologist of the literature supporting current RAI use in hyperthyroidism and new developments in limiting the radiation exposure to the patients with differentiated thyroid cancer.

Authors+Show Affiliations

Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118, USA. stlee@bmc.org

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22914564

Citation

Lee, Stephanie L.. "Radioactive Iodine Therapy." Current Opinion in Endocrinology, Diabetes, and Obesity, vol. 19, no. 5, 2012, pp. 420-8.
Lee SL. Radioactive iodine therapy. Curr Opin Endocrinol Diabetes Obes. 2012;19(5):420-8.
Lee, S. L. (2012). Radioactive iodine therapy. Current Opinion in Endocrinology, Diabetes, and Obesity, 19(5), pp. 420-8. doi:10.1097/MED.0b013e328357fa0c.
Lee SL. Radioactive Iodine Therapy. Curr Opin Endocrinol Diabetes Obes. 2012;19(5):420-8. PubMed PMID: 22914564.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Radioactive iodine therapy. A1 - Lee,Stephanie L, PY - 2012/8/24/entrez PY - 2012/8/24/pubmed PY - 2013/1/16/medline SP - 420 EP - 8 JF - Current opinion in endocrinology, diabetes, and obesity JO - Curr Opin Endocrinol Diabetes Obes VL - 19 IS - 5 N2 - PURPOSE OF REVIEW: Review of the management decisions that must be made by the endocrinologist during the use of radioactive iodine (RAI) therapy of hyperthyroidism and differentiated thyroid cancer. RECENT FINDINGS: Since the 1940s radioactive (131)I (RAI) therapy has been a major component of the treatment of hyperthyroidism and differentiated thyroid cancer. RAI is the most common definitive treatment of hyperthyroidism. Pretherapy decisions including use of antithyroid medication and low-iodine diet will be discussed with the relevant supportive literature. The method of semi-quantitative calculation used for RAI treatment of hyperthyroidism will be described. Evidence-based guideline for the management of differentiated thyroid cancer by the American Thyroid Association, new drug development and recent randomized controlled trials have changed current practice of how RAI is used for remnant ablation and adjuvant therapy of differentiated thyroid cancer. SUMMARY: RAI is a common tool for the endocrinologist in the management of hyperthyroidism and differentiated thyroid cancer. Review of the management decisions and practice of RAI therapy will educate the endocrinologist of the literature supporting current RAI use in hyperthyroidism and new developments in limiting the radiation exposure to the patients with differentiated thyroid cancer. SN - 1752-2978 UR - https://www.unboundmedicine.com/medline/citation/22914564/Radioactive_iodine_therapy_ L2 - http://Insights.ovid.com/pubmed?pmid=22914564 DB - PRIME DP - Unbound Medicine ER -