Tags

Type your tag names separated by a space and hit enter

Control of shivering with clonidine, butorphanol, and tramadol under spinal anesthesia: a comparative study.
Local Reg Anesth. 2011; 4:29-34.LR

Abstract

INTRODUCTION

The present study was designed to evaluate the efficacy of clonidine, butorphanol, and tramadol in control of shivering under spinal anesthesia, and to compare their side effects.

METHODS

This randomized, prospective study was conducted in 90 patients who developed shivering under spinal anesthesia during various abdominal or orthopedic surgery procedures. On shivering, patients were randomly allocated to receive an intravenous, 1 mL bolus dose of 50 mg tramadol, or 1 mg butorphanol, or 150 μg clonidine, in a double blinded manner. Control of shivering, time taken for cessation, recurrence, hemodynamic changes, axillary temperatures, and side effects were noted and compared for all 3 groups. Collected data were analyzed using appropriate statistical tests.

RESULTS

Butorphanol and tramadol were more effective than clonidine in suppressing shivering. Butorphanol, tramadol, and clonidine completely controlled rigors in 83%, 73%, and 53% of cases, respectively, and incompletely suppressed rigors in 16%, 26%, and 46% of cases, respectively. Time taken to terminate rigors was significantly higher for clonidine (3.3 ± 0.9 minutes) than for butorphanol and tramadol (2.1 ± 1.0 minutes and 1.8 ± 0.5 minutes; P < 0.001).

CONCLUSION

Butorphanol had an edge over tramadol in controlling shivering with lower chances of recurrence, though both were superior to clonidine for this purpose with an early onset of action. We conclude that both these opioids control rigors better than α-2 agonists.

Authors+Show Affiliations

Department of Anaesthesiology, Teerthanker Mahaveer Medical College Moradabad, India.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22915890

Citation

Bansal, Pranav, and Gaurav Jain. "Control of Shivering With Clonidine, Butorphanol, and Tramadol Under Spinal Anesthesia: a Comparative Study." Local and Regional Anesthesia, vol. 4, 2011, pp. 29-34.
Bansal P, Jain G. Control of shivering with clonidine, butorphanol, and tramadol under spinal anesthesia: a comparative study. Local and regional anesthesia. 2011;4:29-34.
Bansal, P., & Jain, G. (2011). Control of shivering with clonidine, butorphanol, and tramadol under spinal anesthesia: a comparative study. Local and Regional Anesthesia, 4, 29-34. https://doi.org/10.2147/LRA.S15366
Bansal P, Jain G. Control of Shivering With Clonidine, Butorphanol, and Tramadol Under Spinal Anesthesia: a Comparative Study. Local and regional anesthesia. 2011;4:29-34. PubMed PMID: 22915890.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Control of shivering with clonidine, butorphanol, and tramadol under spinal anesthesia: a comparative study. AU - Bansal,Pranav, AU - Jain,Gaurav, Y1 - 2011/08/10/ PY - 2012/8/24/entrez PY - 2011/1/1/pubmed PY - 2011/1/1/medline KW - butorphanol KW - clonidine KW - perioperative shivering KW - spinal anesthesia KW - thermoregulatory center KW - tramadol SP - 29 EP - 34 JF - Local and regional anesthesia VL - 4 N2 - INTRODUCTION: The present study was designed to evaluate the efficacy of clonidine, butorphanol, and tramadol in control of shivering under spinal anesthesia, and to compare their side effects. METHODS: This randomized, prospective study was conducted in 90 patients who developed shivering under spinal anesthesia during various abdominal or orthopedic surgery procedures. On shivering, patients were randomly allocated to receive an intravenous, 1 mL bolus dose of 50 mg tramadol, or 1 mg butorphanol, or 150 μg clonidine, in a double blinded manner. Control of shivering, time taken for cessation, recurrence, hemodynamic changes, axillary temperatures, and side effects were noted and compared for all 3 groups. Collected data were analyzed using appropriate statistical tests. RESULTS: Butorphanol and tramadol were more effective than clonidine in suppressing shivering. Butorphanol, tramadol, and clonidine completely controlled rigors in 83%, 73%, and 53% of cases, respectively, and incompletely suppressed rigors in 16%, 26%, and 46% of cases, respectively. Time taken to terminate rigors was significantly higher for clonidine (3.3 ± 0.9 minutes) than for butorphanol and tramadol (2.1 ± 1.0 minutes and 1.8 ± 0.5 minutes; P < 0.001). CONCLUSION: Butorphanol had an edge over tramadol in controlling shivering with lower chances of recurrence, though both were superior to clonidine for this purpose with an early onset of action. We conclude that both these opioids control rigors better than α-2 agonists. SN - 1178-7112 UR - https://www.unboundmedicine.com/medline/citation/22915890/Control_of_shivering_with_clonidine_butorphanol_and_tramadol_under_spinal_anesthesia:_a_comparative_study_ L2 - https://dx.doi.org/10.2147/LRA.S15366 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.