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Evaluation of the new generation dual-lumen catheter for neonatal ECMO.
Perfusion. 2013 Jan; 28(1):26-30.P

Abstract

OBJECTIVES

The purpose of this study was to compare the newly designed dual-lumen venovenous catheter (VR13, OriGen Biomedical, Austin, TX) with the current dual-lumen catheter (VV12, OriGen Biomedical).

METHODS

Five newborn lambs, 1 to 5 days old and weighing 4.2 ± 0.5 kg, were cannulated with the VV13 OriGen catheter and placed on extracorporeal membrane oxygenation (ECMO). ECMO flows were increased from 200 to 600 ml/min, with measurements taken after the changes. The experiment was then repeated using the VV12 catheter.

RESULTS

Recirculation values were equal for both catheters. The pressure drop at the reinfusion port was equal for both catheters at 200 ml/min, increasing to 275 mmHg at 500 ml/min for the VR13 vs. 240 mmHg for the VV12 catheter.

CONCLUSION

These findings indicate that the VR13 catheter resulted in levels of recirculation equal to the VV12. Based on resistance measurements, we do not recommend the use of this new catheter beyond 400 ml/min until minor design changes are made.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Said MM
Department of Neonatology, Children's National Medical Center and The George Washington University School of Medicine, Washington, DC 20010, USA. msaid@childrensnational.org
Rivera O
No affiliation info available
Mikesell GT
No affiliation info available
Rais-Bahrami K
No affiliation info available

MeSH

AnimalsAnimals, NewbornBlood PressureCathetersExtracorporeal Membrane OxygenationSheep

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

eng

PubMed ID

22918933

Citation

Said, M M., et al. "Evaluation of the New Generation Dual-lumen Catheter for Neonatal ECMO." Perfusion, vol. 28, no. 1, 2013, pp. 26-30.
Said MM, Rivera O, Mikesell GT, et al. Evaluation of the new generation dual-lumen catheter for neonatal ECMO. Perfusion. 2013;28(1):26-30.
Said, M. M., Rivera, O., Mikesell, G. T., & Rais-Bahrami, K. (2013). Evaluation of the new generation dual-lumen catheter for neonatal ECMO. Perfusion, 28(1), 26-30. https://doi.org/10.1177/0267659112458136
Said MM, et al. Evaluation of the New Generation Dual-lumen Catheter for Neonatal ECMO. Perfusion. 2013;28(1):26-30. PubMed PMID: 22918933.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of the new generation dual-lumen catheter for neonatal ECMO. AU - Said,M M, AU - Rivera,O, AU - Mikesell,G T, AU - Rais-Bahrami,K, Y1 - 2012/08/22/ PY - 2012/8/25/entrez PY - 2012/8/25/pubmed PY - 2013/6/8/medline SP - 26 EP - 30 JF - Perfusion JO - Perfusion VL - 28 IS - 1 N2 - OBJECTIVES: The purpose of this study was to compare the newly designed dual-lumen venovenous catheter (VR13, OriGen Biomedical, Austin, TX) with the current dual-lumen catheter (VV12, OriGen Biomedical). METHODS: Five newborn lambs, 1 to 5 days old and weighing 4.2 ± 0.5 kg, were cannulated with the VV13 OriGen catheter and placed on extracorporeal membrane oxygenation (ECMO). ECMO flows were increased from 200 to 600 ml/min, with measurements taken after the changes. The experiment was then repeated using the VV12 catheter. RESULTS: Recirculation values were equal for both catheters. The pressure drop at the reinfusion port was equal for both catheters at 200 ml/min, increasing to 275 mmHg at 500 ml/min for the VR13 vs. 240 mmHg for the VV12 catheter. CONCLUSION: These findings indicate that the VR13 catheter resulted in levels of recirculation equal to the VV12. Based on resistance measurements, we do not recommend the use of this new catheter beyond 400 ml/min until minor design changes are made. SN - 1477-111X UR - https://www.unboundmedicine.com/medline/citation/22918933/Evaluation_of_the_new_generation_dual_lumen_catheter_for_neonatal_ECMO_ DB - PRIME DP - Unbound Medicine ER -