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Ectopic pituitary adenoma with empty sella in the setting of MEN-1 syndrome: detection with 68Ga-DOTANOC PET/CT.
Jpn J Radiol. 2012 Nov; 30(9):783-6.JJ

Abstract

Patients with multiple endocrine neoplasia type-1 syndromes are known to have neuroendocrine tumors (NETs) involving the pituitary and gastroenteropancreatic region, in addition to the presence of parathyroid abnormalities. In rare instances adenomas in the ectopic pituitary gland have been reported. As pituitary gland and pituitary adenomas are known to express SSTRs, somatostatin receptor scintigraphy can be used for imaging. Somatostatin receptor-based PET/CT imaging using 68Ga-DOTANOC has become a popular noninvasive imaging modality for evaluation of patients with NETs. The application of 68Ga-DOTANOC PET/CT can be extended to multiple endocrine neoplasia type 1 patients, as is evident from this case study.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Naswa N
Department of Nuclear Medicine, All India Institute of Medical Sciences, E-81, Ansari Nagar (East), AIIMS Campus, New Delhi 110029, India.
Das CJ
No affiliation info available
Sharma P
No affiliation info available
Karunanithi S
No affiliation info available
Bal C
No affiliation info available
Kumar R
No affiliation info available

MeSH

AgedChoristomaDuodenal DiseasesEmpty Sella SyndromeFemaleHumansMagnetic Resonance ImagingMultimodal ImagingMultiple Endocrine Neoplasia Type 1Neuroendocrine TumorsOrganometallic CompoundsPituitary NeoplasmsPositron-Emission TomographyTomography, X-Ray Computed

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22923184

Citation

Naswa, Niraj, et al. "Ectopic Pituitary Adenoma With Empty Sella in the Setting of MEN-1 Syndrome: Detection With 68Ga-DOTANOC PET/CT." Japanese Journal of Radiology, vol. 30, no. 9, 2012, pp. 783-6.
Naswa N, Das CJ, Sharma P, et al. Ectopic pituitary adenoma with empty sella in the setting of MEN-1 syndrome: detection with 68Ga-DOTANOC PET/CT. Jpn J Radiol. 2012;30(9):783-6.
Naswa, N., Das, C. J., Sharma, P., Karunanithi, S., Bal, C., & Kumar, R. (2012). Ectopic pituitary adenoma with empty sella in the setting of MEN-1 syndrome: detection with 68Ga-DOTANOC PET/CT. Japanese Journal of Radiology, 30(9), 783-6. https://doi.org/10.1007/s11604-012-0117-0
Naswa N, et al. Ectopic Pituitary Adenoma With Empty Sella in the Setting of MEN-1 Syndrome: Detection With 68Ga-DOTANOC PET/CT. Jpn J Radiol. 2012;30(9):783-6. PubMed PMID: 22923184.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ectopic pituitary adenoma with empty sella in the setting of MEN-1 syndrome: detection with 68Ga-DOTANOC PET/CT. AU - Naswa,Niraj, AU - Das,Chandan Jyoti, AU - Sharma,Punit, AU - Karunanithi,Sellam, AU - Bal,Chandrasekhar, AU - Kumar,Rakesh, Y1 - 2012/08/28/ PY - 2012/04/20/received PY - 2012/08/06/accepted PY - 2012/8/28/entrez PY - 2012/8/28/pubmed PY - 2013/4/30/medline SP - 783 EP - 6 JF - Japanese journal of radiology JO - Jpn J Radiol VL - 30 IS - 9 N2 - Patients with multiple endocrine neoplasia type-1 syndromes are known to have neuroendocrine tumors (NETs) involving the pituitary and gastroenteropancreatic region, in addition to the presence of parathyroid abnormalities. In rare instances adenomas in the ectopic pituitary gland have been reported. As pituitary gland and pituitary adenomas are known to express SSTRs, somatostatin receptor scintigraphy can be used for imaging. Somatostatin receptor-based PET/CT imaging using 68Ga-DOTANOC has become a popular noninvasive imaging modality for evaluation of patients with NETs. The application of 68Ga-DOTANOC PET/CT can be extended to multiple endocrine neoplasia type 1 patients, as is evident from this case study. SN - 1867-108X UR - https://www.unboundmedicine.com/medline/citation/22923184/Ectopic_pituitary_adenoma_with_empty_sella_in_the_setting_of_MEN_1_syndrome:_detection_with_68Ga_DOTANOC_PET/CT_ L2 - https://dx.doi.org/10.1007/s11604-012-0117-0 DB - PRIME DP - Unbound Medicine ER -