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Analysis of phenolic composition of Noble muscadine (Vitis rotundifolia) by HPLC-MS and the relationship to its antioxidant capacity.
J Food Sci. 2012 Oct; 77(10):C1115-23.JF

Abstract

Phenolic compounds and anthocyanins in muscadines have attracted much attention due to their diverse biological activities. With bioassays of antioxidant activities in terms of total phenolic content (TPC), total anthocyanin content (TAC), total procyanidin content (TPA), oxygen radical absorbance capacity (ORAC), and ferric reducing antioxidant power (FRAP) of different parts of the Noble muscadine, the butanol (BuOH) extract of the muscadine skin showed the highest TPC (317.91 ± 1.83 mg GAE/100 g FW), which might be ascribed to its high TAC of 227.06 ± 1.29 mg/100 g fresh weight (FW). The ethyl acetate (EtOAc) extract of the muscadine seed contained the highest TPA (55.30 ± 0.63 mg CE/100 g FW). Correlation analyses demonstrated a significant linear relationship of TPC and TAC compared to their ORAC and FRAP values within the range of R(2) from 0.9283 to 0.9936, which suggested that phenolics and anthocyanins in the extracts contributed significantly to their antioxidant potential. Nineteen individual phenolics and 5 anthocyanins were identified by HPLC-MS, which indicated different chemical profiles of anthocyanins and other phenolics in the muscadine extracts.

PRACTICAL APPLICATION

The paper has provided rich information of bioactive phytochemical profiles in different solvent extracts and their correlation with the antioxidant activity in the muscadine that is a very special regional fruit in U.S. Its high content of phenolic compounds demonstrates that muscadine could be beneficial to human health.

Authors+Show Affiliations

Department of Food, Nutrition, and Packaging Sciences, Clemson University, Clemson, SC 29634, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22924759

Citation

You, Qi, et al. "Analysis of Phenolic Composition of Noble Muscadine (Vitis Rotundifolia) By HPLC-MS and the Relationship to Its Antioxidant Capacity." Journal of Food Science, vol. 77, no. 10, 2012, pp. C1115-23.
You Q, Chen F, Wang X, et al. Analysis of phenolic composition of Noble muscadine (Vitis rotundifolia) by HPLC-MS and the relationship to its antioxidant capacity. J Food Sci. 2012;77(10):C1115-23.
You, Q., Chen, F., Wang, X., Sharp, J. L., & You, Y. (2012). Analysis of phenolic composition of Noble muscadine (Vitis rotundifolia) by HPLC-MS and the relationship to its antioxidant capacity. Journal of Food Science, 77(10), C1115-23. https://doi.org/10.1111/j.1750-3841.2012.02888.x
You Q, et al. Analysis of Phenolic Composition of Noble Muscadine (Vitis Rotundifolia) By HPLC-MS and the Relationship to Its Antioxidant Capacity. J Food Sci. 2012;77(10):C1115-23. PubMed PMID: 22924759.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Analysis of phenolic composition of Noble muscadine (Vitis rotundifolia) by HPLC-MS and the relationship to its antioxidant capacity. AU - You,Qi, AU - Chen,Feng, AU - Wang,Xi, AU - Sharp,Julia L, AU - You,Yuru, Y1 - 2012/08/27/ PY - 2012/8/29/entrez PY - 2012/8/29/pubmed PY - 2013/4/10/medline SP - C1115 EP - 23 JF - Journal of food science JO - J Food Sci VL - 77 IS - 10 N2 - UNLABELLED: Phenolic compounds and anthocyanins in muscadines have attracted much attention due to their diverse biological activities. With bioassays of antioxidant activities in terms of total phenolic content (TPC), total anthocyanin content (TAC), total procyanidin content (TPA), oxygen radical absorbance capacity (ORAC), and ferric reducing antioxidant power (FRAP) of different parts of the Noble muscadine, the butanol (BuOH) extract of the muscadine skin showed the highest TPC (317.91 ± 1.83 mg GAE/100 g FW), which might be ascribed to its high TAC of 227.06 ± 1.29 mg/100 g fresh weight (FW). The ethyl acetate (EtOAc) extract of the muscadine seed contained the highest TPA (55.30 ± 0.63 mg CE/100 g FW). Correlation analyses demonstrated a significant linear relationship of TPC and TAC compared to their ORAC and FRAP values within the range of R(2) from 0.9283 to 0.9936, which suggested that phenolics and anthocyanins in the extracts contributed significantly to their antioxidant potential. Nineteen individual phenolics and 5 anthocyanins were identified by HPLC-MS, which indicated different chemical profiles of anthocyanins and other phenolics in the muscadine extracts. PRACTICAL APPLICATION: The paper has provided rich information of bioactive phytochemical profiles in different solvent extracts and their correlation with the antioxidant activity in the muscadine that is a very special regional fruit in U.S. Its high content of phenolic compounds demonstrates that muscadine could be beneficial to human health. SN - 1750-3841 UR - https://www.unboundmedicine.com/medline/citation/22924759/Analysis_of_phenolic_composition_of_Noble_muscadine__Vitis_rotundifolia__by_HPLC_MS_and_the_relationship_to_its_antioxidant_capacity_ L2 - https://doi.org/10.1111/j.1750-3841.2012.02888.x DB - PRIME DP - Unbound Medicine ER -