Tags

Type your tag names separated by a space and hit enter

Informatics in radiology: development of a research PACS for analysis of functional imaging data in clinical research and clinical trials.
Radiographics. 2012 Nov-Dec; 32(7):2135-50.R

Abstract

Picture archiving and communication systems (PACS) provide limited flexibility for the development of novel research methods. By contrast, the research model of data access is more flexible but has vulnerabilities in numerous areas. No single monolithic application can fulfill the diverse and rapidly changing needs of the clinical imaging research community. Instead, the focus should be on the interoperability of preexisting systems. To a large extent, this can be achieved by means of a unified interface for storing and retrieving data. The concept of a research PACS combines the advantages of the clinical and research models of data access while eliminating the disadvantages. A research PACS streamlines the data management process. Instead of a single software program, it consists of a confederation of independent applications brought together by the ability to store and retrieve data in a common database. A prototype research PACS has been developed that is based on the Extensible Neuroimaging Archive Toolkit (XNAT) in association with two new in-house tools: a data selection tool and a data archiving tool. By taking as an example the comparison of regions of interest in multifunctional liver data, it was demonstrated that this framework allows a number of in-house and open-source applications originally designed to work on a stand-alone basis to be integrated into a unified workflow, with minimal redevelopment effort.

Links

Publisher Full Text

Authors+Show Affiliations

Doran SJ
Cancer Research UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research, 15 Cotswold Rd, Sutton SM2 5NG, England. Simon.Doran@icr.ac.uk
d'Arcy J
No affiliation info available
Collins DJ
No affiliation info available
Andriantsimiavona R
No affiliation info available
Orton M
No affiliation info available
Koh DM
No affiliation info available
Leach MO
No affiliation info available

MeSH

Biomedical ResearchClinical Trials as TopicInternetMedical InformaticsMedical Records Systems, ComputerizedRadiology Information SystemsSystems IntegrationUnited StatesUser-Computer Interface

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22929148

Citation

Doran, Simon J., et al. "Informatics in Radiology: Development of a Research PACS for Analysis of Functional Imaging Data in Clinical Research and Clinical Trials." Radiographics : a Review Publication of the Radiological Society of North America, Inc, vol. 32, no. 7, 2012, pp. 2135-50.
Doran SJ, d'Arcy J, Collins DJ, et al. Informatics in radiology: development of a research PACS for analysis of functional imaging data in clinical research and clinical trials. Radiographics. 2012;32(7):2135-50.
Doran, S. J., d'Arcy, J., Collins, D. J., Andriantsimiavona, R., Orton, M., Koh, D. M., & Leach, M. O. (2012). Informatics in radiology: development of a research PACS for analysis of functional imaging data in clinical research and clinical trials. Radiographics : a Review Publication of the Radiological Society of North America, Inc, 32(7), 2135-50. https://doi.org/10.1148/rg.327115138
Doran SJ, et al. Informatics in Radiology: Development of a Research PACS for Analysis of Functional Imaging Data in Clinical Research and Clinical Trials. Radiographics. 2012 Nov-Dec;32(7):2135-50. PubMed PMID: 22929148.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Informatics in radiology: development of a research PACS for analysis of functional imaging data in clinical research and clinical trials. AU - Doran,Simon J, AU - d'Arcy,James, AU - Collins,David J, AU - Andriantsimiavona,Rado, AU - Orton,Matthew, AU - Koh,Dow-Mu, AU - Leach,Martin O, Y1 - 2012/08/28/ PY - 2012/8/30/entrez PY - 2012/8/30/pubmed PY - 2013/5/31/medline SP - 2135 EP - 50 JF - Radiographics : a review publication of the Radiological Society of North America, Inc JO - Radiographics VL - 32 IS - 7 N2 - Picture archiving and communication systems (PACS) provide limited flexibility for the development of novel research methods. By contrast, the research model of data access is more flexible but has vulnerabilities in numerous areas. No single monolithic application can fulfill the diverse and rapidly changing needs of the clinical imaging research community. Instead, the focus should be on the interoperability of preexisting systems. To a large extent, this can be achieved by means of a unified interface for storing and retrieving data. The concept of a research PACS combines the advantages of the clinical and research models of data access while eliminating the disadvantages. A research PACS streamlines the data management process. Instead of a single software program, it consists of a confederation of independent applications brought together by the ability to store and retrieve data in a common database. A prototype research PACS has been developed that is based on the Extensible Neuroimaging Archive Toolkit (XNAT) in association with two new in-house tools: a data selection tool and a data archiving tool. By taking as an example the comparison of regions of interest in multifunctional liver data, it was demonstrated that this framework allows a number of in-house and open-source applications originally designed to work on a stand-alone basis to be integrated into a unified workflow, with minimal redevelopment effort. SN - 1527-1323 UR - https://www.unboundmedicine.com/medline/citation/22929148/Informatics_in_radiology:_development_of_a_research_PACS_for_analysis_of_functional_imaging_data_in_clinical_research_and_clinical_trials_ L2 - https://pubs.rsna.org/doi/10.1148/rg.327115138?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -