Tags

Type your tag names separated by a space and hit enter

The incidence of rheumatoid arthritis in the UK: comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register.
Ann Rheum Dis. 2013 Aug; 72(8):1315-20.AR

Abstract

OBJECTIVES

The development of new classification criteria for rheumatoid arthritis (RA) calls for a re-estimation of RA incidence rates. The objectives of this study were to estimate the age and sex-specific incidence rates (IR) of RA in Norfolk, England using the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism criteria, and to compare those with IRs estimated using the 1987 ACR criteria.

SETTING

The Norfolk Arthritis Register (NOAR), a large primary care inception cohort of patients with inflammatory oligo- and polyarthritis (IP) aged ≥ 16.

METHODS

All patients notified to NOAR from 1990-5 with symptom onset in 1990 were included. The former Norwich Health Authority population was the denominator. Age and sex specific IRs using 1987 and 2010 classification criteria were calculated at baseline visit, annually for the first 3 years and at 5 years.

RESULTS

260 patients were notified to NOAR with symptom onset in 1990 and without an alternative diagnosis. IRs applying the 2010 criteria at baseline were 54/100 000 for women and 25/100 000 for men. Age and sex-specific IRs using the 2010 classification criteria at baseline were similar to cumulative IRs applying the 1987 criteria up to 5 years. However, some patients only ever satisfied one set of criteria and a proportion of IA patients (20%) did not satisfy either criteria set over 5 years.

CONCLUSIONS

The 2010 criteria classify similar numbers of patients as having RA at baseline, as the 1987 criteria would have taken up to 5 years to identify.

Authors+Show Affiliations

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22945499

Citation

Humphreys, Jennifer H., et al. "The Incidence of Rheumatoid Arthritis in the UK: Comparisons Using the 2010 ACR/EULAR Classification Criteria and the 1987 ACR Classification Criteria. Results From the Norfolk Arthritis Register." Annals of the Rheumatic Diseases, vol. 72, no. 8, 2013, pp. 1315-20.
Humphreys JH, Verstappen SM, Hyrich KL, et al. The incidence of rheumatoid arthritis in the UK: comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register. Ann Rheum Dis. 2013;72(8):1315-20.
Humphreys, J. H., Verstappen, S. M., Hyrich, K. L., Chipping, J. R., Marshall, T., & Symmons, D. P. (2013). The incidence of rheumatoid arthritis in the UK: comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register. Annals of the Rheumatic Diseases, 72(8), 1315-20. https://doi.org/10.1136/annrheumdis-2012-201960
Humphreys JH, et al. The Incidence of Rheumatoid Arthritis in the UK: Comparisons Using the 2010 ACR/EULAR Classification Criteria and the 1987 ACR Classification Criteria. Results From the Norfolk Arthritis Register. Ann Rheum Dis. 2013;72(8):1315-20. PubMed PMID: 22945499.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The incidence of rheumatoid arthritis in the UK: comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register. AU - Humphreys,Jennifer H, AU - Verstappen,Suzanne M M, AU - Hyrich,Kimme L, AU - Chipping,Jacqueline R, AU - Marshall,Tarnya, AU - Symmons,Deborah P M, Y1 - 2012/09/03/ PY - 2012/9/5/entrez PY - 2012/9/5/pubmed PY - 2013/9/21/medline KW - Early Rheumatoid Arthritis KW - Epidemiology KW - Rheumatoid Arthritis SP - 1315 EP - 20 JF - Annals of the rheumatic diseases JO - Ann Rheum Dis VL - 72 IS - 8 N2 - OBJECTIVES: The development of new classification criteria for rheumatoid arthritis (RA) calls for a re-estimation of RA incidence rates. The objectives of this study were to estimate the age and sex-specific incidence rates (IR) of RA in Norfolk, England using the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism criteria, and to compare those with IRs estimated using the 1987 ACR criteria. SETTING: The Norfolk Arthritis Register (NOAR), a large primary care inception cohort of patients with inflammatory oligo- and polyarthritis (IP) aged ≥ 16. METHODS: All patients notified to NOAR from 1990-5 with symptom onset in 1990 were included. The former Norwich Health Authority population was the denominator. Age and sex specific IRs using 1987 and 2010 classification criteria were calculated at baseline visit, annually for the first 3 years and at 5 years. RESULTS: 260 patients were notified to NOAR with symptom onset in 1990 and without an alternative diagnosis. IRs applying the 2010 criteria at baseline were 54/100 000 for women and 25/100 000 for men. Age and sex-specific IRs using the 2010 classification criteria at baseline were similar to cumulative IRs applying the 1987 criteria up to 5 years. However, some patients only ever satisfied one set of criteria and a proportion of IA patients (20%) did not satisfy either criteria set over 5 years. CONCLUSIONS: The 2010 criteria classify similar numbers of patients as having RA at baseline, as the 1987 criteria would have taken up to 5 years to identify. SN - 1468-2060 UR - https://www.unboundmedicine.com/medline/citation/22945499/The_incidence_of_rheumatoid_arthritis_in_the_UK:_comparisons_using_the_2010_ACR/EULAR_classification_criteria_and_the_1987_ACR_classification_criteria__Results_from_the_Norfolk_Arthritis_Register_ L2 - http://ard.bmj.com/lookup/pmidlookup?view=long&pmid=22945499 DB - PRIME DP - Unbound Medicine ER -