TY - JOUR T1 - Long-term outcome of preoperative disrupted inner/outer segment junctions assessed using spectral-domain optical coherence tomography in patients with idiopathic epiretinal membrane. AU - Inoue,Maiko, AU - Arakawa,Akira, AU - Yamane,Shin, AU - Kadonosono,Kazuaki, Y1 - 2012/08/29/ PY - 2012/05/07/received PY - 2012/06/26/accepted PY - 2012/9/6/entrez PY - 2012/9/6/pubmed PY - 2013/4/17/medline SP - 222 EP - 8 JF - Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde JO - Ophthalmologica VL - 228 IS - 4 N2 - PURPOSE: To evaluate the anatomic and functional outcomes as assessed by spectral-domain optical coherence tomography in patients with a preoperative disrupted or irregular photoreceptor inner/outer segment (IS/OS) junction who underwent idiopathic epiretinal membrane (ERM) surgery and were followed for at least 2 years. METHODS: We retrospectively studied all of the patients with idiopathic ERM who had a preoperative disrupted IS/OS junction and were scheduled to undergo a transconjunctival 25-gauge vitrectomy between September 2007 and October 2009. All of the patients who had a 2-year or longer follow-up period were included in the study. The best-corrected visual acuity (BCVA) and structural changes in the IS/OS junction were examined before and 3, 6, 12, and 24 months after surgery. Furthermore, patients were divided into two groups based on whether the preoperative disrupted IS/OS junction had been caused by a lamellar macular hole (LMH type) or swelling as a result of ERM traction (S type). Morphologic changes in the IS/OS junctions of each type were also investigated. RESULTS: A total of 17 patients were identified in this study. Overall, a significantly better postoperative BCVA was seen after surgery; in particular, the BCVA at 24 months was significantly better than that at 12 months (p=0.018). Although the disrupted IS/OS junction appeared normal in 1 out of 17 eyes at 12 months, 7 eyes appeared normal at 24 months. These 7 eyes showed significant postoperative improvement in BCVA compared with the remaining 10 eyes (p=0.045, p=0.021, p=0.019, and p=0.015 at 3, 6, 12, and 24 months, respectively). The preoperative disrupted IS/OS junction was classified as LMH type in 8 eyes and as S type in 9 eyes. The LMH type, rather than the S type, tended to show a persistently disrupted IS/OS junction at 24 months, although the difference was not significant. CONCLUSION: Anatomic and functional recovery of preoperative disrupted IS/OS junctions can be acquired even after more than 1 year postoperatively. However, eyes with persistent irregularities of the IS/OS junction at a 2-year follow-up, especially those with LMH type irregularities, might have a limited visual improvement. SN - 1423-0267 UR - https://www.unboundmedicine.com/medline/citation/22948332/Long_term_outcome_of_preoperative_disrupted_inner/outer_segment_junctions_assessed_using_spectral_domain_optical_coherence_tomography_in_patients_with_idiopathic_epiretinal_membrane_ L2 - https://www.karger.com?DOI=10.1159/000341606 DB - PRIME DP - Unbound Medicine ER -