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Association between salivary pH and metabolic syndrome in women: a cross-sectional study.
BMC Oral Health. 2012 Sep 08; 12:40.BO

Abstract

BACKGROUND

The salivary flow rate is an important determinant of salivary pH. It is influenced by several metabolic syndrome (MetS) components as well as the menopausal status. The cluster of cardiometabolic risk factors that characterizes the MetS could be exacerbated following menopause. The objective of this study was therefore to document the association between salivary pH and MetS expression in women according to the menopausal status.

METHODS

In this cross-sectional study, unstimulated saliva collection was performed on 198 Caucasian women of French-Canadian origin of which 55 were premenopausal women (PMW) and 143 menopausal women (MW). Student's t test, ANOVA and correlation analyses were used to assess the association between salivary pH and MetS components.

RESULTS

The salivary pH level was significantly correlated with several MetS covariates, namely triglycerides (TG), apolipoprotein B (apo B) and plasma glucose concentrations as well as waist circumference and the number of MetS components present in the whole sample and PMW only. Mean pH levels decreased as the number of MetS components increased (p = 0.004). The correlations between salivary pH and variables associated with MetS components tended to be stronger in PMW. The proportion of the variance (R2) of salivary pH explained by MetS-related variables in PMW, MW and the whole sample was 23.6% (p = 0.041), 18.1% and 17.0% (p < 0.001) respectively.

CONCLUSIONS

The increasing prevalence of obesity calls for the development of new technologies to more easily monitor health status without increasing the burden of healthcare costs. As such, the salivary pH could be an inexpensive screening tool. These exploratory data suggest that salivary pH may be a significant correlate of the expression of MetS components. However, other studies with different populations are needed to confirm these findings before our observations lead to practical use in clinical settings.

Authors+Show Affiliations

Université de Montréal, Department of Medicine, ECOGENE-21 Clinical Research Center; Chicoutimi Hospital, 305 St-Vallier Street, Chicoutimi (Québec), Saguenay, Canada.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

22958748

Citation

Tremblay, Monique, et al. "Association Between Salivary pH and Metabolic Syndrome in Women: a Cross-sectional Study." BMC Oral Health, vol. 12, 2012, p. 40.
Tremblay M, Brisson D, Gaudet D. Association between salivary pH and metabolic syndrome in women: a cross-sectional study. BMC Oral Health. 2012;12:40.
Tremblay, M., Brisson, D., & Gaudet, D. (2012). Association between salivary pH and metabolic syndrome in women: a cross-sectional study. BMC Oral Health, 12, 40. https://doi.org/10.1186/1472-6831-12-40
Tremblay M, Brisson D, Gaudet D. Association Between Salivary pH and Metabolic Syndrome in Women: a Cross-sectional Study. BMC Oral Health. 2012 Sep 8;12:40. PubMed PMID: 22958748.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association between salivary pH and metabolic syndrome in women: a cross-sectional study. AU - Tremblay,Monique, AU - Brisson,Diane, AU - Gaudet,Daniel, Y1 - 2012/09/08/ PY - 2011/12/22/received PY - 2012/08/30/accepted PY - 2012/9/11/entrez PY - 2012/9/11/pubmed PY - 2013/3/13/medline SP - 40 EP - 40 JF - BMC oral health JO - BMC Oral Health VL - 12 N2 - BACKGROUND: The salivary flow rate is an important determinant of salivary pH. It is influenced by several metabolic syndrome (MetS) components as well as the menopausal status. The cluster of cardiometabolic risk factors that characterizes the MetS could be exacerbated following menopause. The objective of this study was therefore to document the association between salivary pH and MetS expression in women according to the menopausal status. METHODS: In this cross-sectional study, unstimulated saliva collection was performed on 198 Caucasian women of French-Canadian origin of which 55 were premenopausal women (PMW) and 143 menopausal women (MW). Student's t test, ANOVA and correlation analyses were used to assess the association between salivary pH and MetS components. RESULTS: The salivary pH level was significantly correlated with several MetS covariates, namely triglycerides (TG), apolipoprotein B (apo B) and plasma glucose concentrations as well as waist circumference and the number of MetS components present in the whole sample and PMW only. Mean pH levels decreased as the number of MetS components increased (p = 0.004). The correlations between salivary pH and variables associated with MetS components tended to be stronger in PMW. The proportion of the variance (R2) of salivary pH explained by MetS-related variables in PMW, MW and the whole sample was 23.6% (p = 0.041), 18.1% and 17.0% (p < 0.001) respectively. CONCLUSIONS: The increasing prevalence of obesity calls for the development of new technologies to more easily monitor health status without increasing the burden of healthcare costs. As such, the salivary pH could be an inexpensive screening tool. These exploratory data suggest that salivary pH may be a significant correlate of the expression of MetS components. However, other studies with different populations are needed to confirm these findings before our observations lead to practical use in clinical settings. SN - 1472-6831 UR - https://www.unboundmedicine.com/medline/citation/22958748/Association_between_salivary_pH_and_metabolic_syndrome_in_women:_a_cross_sectional_study_ L2 - https://bmcoralhealth.biomedcentral.com/articles/10.1186/1472-6831-12-40 DB - PRIME DP - Unbound Medicine ER -