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Pygmy rattlesnake envenomation treated with Crotalidae Polyvalent Immune Fab Antivenom.
Toxicon. 2012 Dec 01; 60(7):1287-9.T

Abstract

Documented envenomations by the pygmy rattlesnake (Sistrurus miliarius barbouri) are rare. While there have been no documented fatalities, several older case reports describe significant morbidity. We describe the first known case of pygmy rattlesnake envenomation that was treated with Crotalidae Polyvalent Immune Fab Antivenom (CroFab®).

CASE

A 28-year-old man with no significant past medical history presented after being envenomated on the right hand by his friend's pet pygmy rattlesnake. He developed swelling and pain in his hand and forearm. He responded well to a ten vial loading dose and a 18 h maintenance protocol of CroFab and was discharged the following day without developing any hematological or electrolyte derangements.

CONCLUSION

This is the first documented use of CroFab for S. m. barbouri envenomation. The outcome of this case suggests that CroFab is a safe treatment modality in this setting.

Authors+Show Affiliations

Division of Medical Toxicology, Department of Emergency Medicine, University of Pittsburgh Medical Center, PUH South Tower, Suite M2935, Pittsburgh, PA 15213, USA. kingam@upmc.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22963729

Citation

King, Andrew M., et al. "Pygmy Rattlesnake Envenomation Treated With Crotalidae Polyvalent Immune Fab Antivenom." Toxicon : Official Journal of the International Society On Toxinology, vol. 60, no. 7, 2012, pp. 1287-9.
King AM, Crim WS, Menke NB, et al. Pygmy rattlesnake envenomation treated with Crotalidae Polyvalent Immune Fab Antivenom. Toxicon. 2012;60(7):1287-9.
King, A. M., Crim, W. S., Menke, N. B., & Pizon, A. F. (2012). Pygmy rattlesnake envenomation treated with Crotalidae Polyvalent Immune Fab Antivenom. Toxicon : Official Journal of the International Society On Toxinology, 60(7), 1287-9. https://doi.org/10.1016/j.toxicon.2012.08.007
King AM, et al. Pygmy Rattlesnake Envenomation Treated With Crotalidae Polyvalent Immune Fab Antivenom. Toxicon. 2012 Dec 1;60(7):1287-9. PubMed PMID: 22963729.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pygmy rattlesnake envenomation treated with Crotalidae Polyvalent Immune Fab Antivenom. AU - King,Andrew M, AU - Crim,William S, AU - Menke,Nathan B, AU - Pizon,Anthony F, Y1 - 2012/08/30/ PY - 2012/05/02/received PY - 2012/08/09/revised PY - 2012/08/16/accepted PY - 2012/9/12/entrez PY - 2012/9/12/pubmed PY - 2013/3/9/medline SP - 1287 EP - 9 JF - Toxicon : official journal of the International Society on Toxinology JO - Toxicon VL - 60 IS - 7 N2 - UNLABELLED: Documented envenomations by the pygmy rattlesnake (Sistrurus miliarius barbouri) are rare. While there have been no documented fatalities, several older case reports describe significant morbidity. We describe the first known case of pygmy rattlesnake envenomation that was treated with Crotalidae Polyvalent Immune Fab Antivenom (CroFab®). CASE: A 28-year-old man with no significant past medical history presented after being envenomated on the right hand by his friend's pet pygmy rattlesnake. He developed swelling and pain in his hand and forearm. He responded well to a ten vial loading dose and a 18 h maintenance protocol of CroFab and was discharged the following day without developing any hematological or electrolyte derangements. CONCLUSION: This is the first documented use of CroFab for S. m. barbouri envenomation. The outcome of this case suggests that CroFab is a safe treatment modality in this setting. SN - 1879-3150 UR - https://www.unboundmedicine.com/medline/citation/22963729/Pygmy_rattlesnake_envenomation_treated_with_Crotalidae_Polyvalent_Immune_Fab_Antivenom_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0041-0101(12)00720-9 DB - PRIME DP - Unbound Medicine ER -