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Angle closure in the Namil study in central South Korea.
Arch Ophthalmol 2012; 130(9):1177-83AO

Abstract

OBJECTIVE

To assess the prevalence and associated risk factors of angle closure in a defined population as part of the Namil Study.

METHODS

In this cross-sectional epidemiologic study for residents aged 40 years or older in Namil-myon, a rural area in central South Korea, the examination included slitlamp biomicroscopy, applanation tonometry, gonioscopy, autorefraction, fundus photography, corneal thickness measurement, visual field test with frequency-doubling technology, and anterior chamber depth (ACD) and axial length (AL) measurements with partial coherence interferometry. Standard automated field test and optical coherence tomography or scanning laser polarimetry were performed to confirm the glaucomatous visual field/optic disc damage. Angle closure included primary angle-closure suspect (PACS), primary angle closure (PAC), and primary angle-closure glaucoma (PACG). Definitions of PACS, PAC, and PACG were based on the recommendations from the International Society for Geographical &Epidemiological Ophthalmology.

RESULTS

Among the 1426 individuals enrolled for the assessment, with exclusion of cataract surgery, the prevalence rates of PACS, PAC, PACG, and overall angle closure in at least 1 eye were 2.0% (95% CI, 1.3%-2.8%), 0.5% (95% CI, 0.1%-0.9%), 0.7% (95% CI, 0.3%-1.1%), and 3.2% (95% CI, 2.3%-4.2%), respectively. Multivariate analysis found that older age (odds ratio [OR], 1.8797; 95% CI, 1.4624-2.4162), shallower ACD (OR, 0.9982; 95% CI, 0.9977-0.9987), and shorter AL (OR 0.9978; 95% CI, 0.9969-0.9988) (P < .001 for each) were significantly associated with angle closure.

CONCLUSIONS

The overall prevalence of angle closure was 3.2% in the present study. On the basis of these findings, increasing age, shallower ACD, and shorter AL appear to be associated with angle closure. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT00727168.

Authors+Show Affiliations

Department of Ophthalmology, Korea University College of Medicine, Seoul, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22965594

Citation

Kim, Yong Yeon, et al. "Angle Closure in the Namil Study in Central South Korea." Archives of Ophthalmology (Chicago, Ill. : 1960), vol. 130, no. 9, 2012, pp. 1177-83.
Kim YY, Lee JH, Ahn MD, et al. Angle closure in the Namil study in central South Korea. Arch Ophthalmol. 2012;130(9):1177-83.
Kim, Y. Y., Lee, J. H., Ahn, M. D., & Kim, C. Y. (2012). Angle closure in the Namil study in central South Korea. Archives of Ophthalmology (Chicago, Ill. : 1960), 130(9), pp. 1177-83.
Kim YY, et al. Angle Closure in the Namil Study in Central South Korea. Arch Ophthalmol. 2012;130(9):1177-83. PubMed PMID: 22965594.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Angle closure in the Namil study in central South Korea. AU - Kim,Yong Yeon, AU - Lee,Joo Hwa, AU - Ahn,Myung Douk, AU - Kim,Chan Yun, AU - ,, PY - 2012/9/12/entrez PY - 2012/9/12/pubmed PY - 2012/12/10/medline SP - 1177 EP - 83 JF - Archives of ophthalmology (Chicago, Ill. : 1960) JO - Arch. Ophthalmol. VL - 130 IS - 9 N2 - OBJECTIVE: To assess the prevalence and associated risk factors of angle closure in a defined population as part of the Namil Study. METHODS: In this cross-sectional epidemiologic study for residents aged 40 years or older in Namil-myon, a rural area in central South Korea, the examination included slitlamp biomicroscopy, applanation tonometry, gonioscopy, autorefraction, fundus photography, corneal thickness measurement, visual field test with frequency-doubling technology, and anterior chamber depth (ACD) and axial length (AL) measurements with partial coherence interferometry. Standard automated field test and optical coherence tomography or scanning laser polarimetry were performed to confirm the glaucomatous visual field/optic disc damage. Angle closure included primary angle-closure suspect (PACS), primary angle closure (PAC), and primary angle-closure glaucoma (PACG). Definitions of PACS, PAC, and PACG were based on the recommendations from the International Society for Geographical &Epidemiological Ophthalmology. RESULTS: Among the 1426 individuals enrolled for the assessment, with exclusion of cataract surgery, the prevalence rates of PACS, PAC, PACG, and overall angle closure in at least 1 eye were 2.0% (95% CI, 1.3%-2.8%), 0.5% (95% CI, 0.1%-0.9%), 0.7% (95% CI, 0.3%-1.1%), and 3.2% (95% CI, 2.3%-4.2%), respectively. Multivariate analysis found that older age (odds ratio [OR], 1.8797; 95% CI, 1.4624-2.4162), shallower ACD (OR, 0.9982; 95% CI, 0.9977-0.9987), and shorter AL (OR 0.9978; 95% CI, 0.9969-0.9988) (P < .001 for each) were significantly associated with angle closure. CONCLUSIONS: The overall prevalence of angle closure was 3.2% in the present study. On the basis of these findings, increasing age, shallower ACD, and shorter AL appear to be associated with angle closure. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT00727168. SN - 1538-3601 UR - https://www.unboundmedicine.com/medline/citation/22965594/Angle_closure_in_the_Namil_study_in_central_South_Korea_ L2 - https://jamanetwork.com/journals/jamaophthalmology/fullarticle/10.1001/archophthalmol.2012.1470 DB - PRIME DP - Unbound Medicine ER -