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Using timed up-and-go to identify frail members of the older population.
J Gerontol A Biol Sci Med Sci. 2013 Apr; 68(4):441-6.JG

Abstract

BACKGROUND

Fried's definition of frailty is widely used but its measurement is problematic. Timed up-and-go (TUG) is a simple measure of mobility that may be a useful proxy for frailty. Here, we describe the distribution of frailty and TUG in the older population of Ireland and discuss the extent to which TUG identifies the frail and prefrail populations.

METHODS

A total of 1,814 participants of The Irish Longitudinal Study on Ageing aged 65 and older completed a comprehensive health assessment. Frailty was defined by having three or more of low gait speed, low grip strength, unintentional weight loss, self-reported exhaustion, and low physical activity. ROC curves were used to identify how well TUG discriminates the frail and prefrail populations and whether TUG improves on gait speed as a single objective measure of frailty.

RESULTS

Among the Irish population aged 65 and older, 7.7% were frail and 44.0% were prefrail. TUG identifies frail members of the population well (AUC = 0.87) but is less able to discriminate the nonfrail from the prefrail or frail populations (AUC = 0.73). TUG captures the components of frailty that become more common with age but does not discriminate the components that do not, for example, unintended weight loss or exhaustion. There is no advantage in using TUG instead of gait speed with respect to identifying frailty.

CONCLUSIONS

TUG is a sensitive and specific measure of frailty that offers advantages in its measurement where the full application or interpretation of Fried's criteria is impracticable; however, TUG cannot be used to reliably identify prefrail individuals.

Authors+Show Affiliations

The Irish Longitudinal Study on Ageing, Trinity College Dublin, Lincoln Gate, Dublin, Republic of Ireland. george.savva@tcd.ieNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22987796

Citation

Savva, George M., et al. "Using Timed Up-and-go to Identify Frail Members of the Older Population." The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, vol. 68, no. 4, 2013, pp. 441-6.
Savva GM, Donoghue OA, Horgan F, et al. Using timed up-and-go to identify frail members of the older population. J Gerontol A Biol Sci Med Sci. 2013;68(4):441-6.
Savva, G. M., Donoghue, O. A., Horgan, F., O'Regan, C., Cronin, H., & Kenny, R. A. (2013). Using timed up-and-go to identify frail members of the older population. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 68(4), 441-6. https://doi.org/10.1093/gerona/gls190
Savva GM, et al. Using Timed Up-and-go to Identify Frail Members of the Older Population. J Gerontol A Biol Sci Med Sci. 2013;68(4):441-6. PubMed PMID: 22987796.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Using timed up-and-go to identify frail members of the older population. AU - Savva,George M, AU - Donoghue,Orna A, AU - Horgan,Frances, AU - O'Regan,Claire, AU - Cronin,Hilary, AU - Kenny,Rose Anne, Y1 - 2012/09/17/ PY - 2012/9/19/entrez PY - 2012/9/19/pubmed PY - 2013/5/28/medline SP - 441 EP - 6 JF - The journals of gerontology. Series A, Biological sciences and medical sciences JO - J Gerontol A Biol Sci Med Sci VL - 68 IS - 4 N2 - BACKGROUND: Fried's definition of frailty is widely used but its measurement is problematic. Timed up-and-go (TUG) is a simple measure of mobility that may be a useful proxy for frailty. Here, we describe the distribution of frailty and TUG in the older population of Ireland and discuss the extent to which TUG identifies the frail and prefrail populations. METHODS: A total of 1,814 participants of The Irish Longitudinal Study on Ageing aged 65 and older completed a comprehensive health assessment. Frailty was defined by having three or more of low gait speed, low grip strength, unintentional weight loss, self-reported exhaustion, and low physical activity. ROC curves were used to identify how well TUG discriminates the frail and prefrail populations and whether TUG improves on gait speed as a single objective measure of frailty. RESULTS: Among the Irish population aged 65 and older, 7.7% were frail and 44.0% were prefrail. TUG identifies frail members of the population well (AUC = 0.87) but is less able to discriminate the nonfrail from the prefrail or frail populations (AUC = 0.73). TUG captures the components of frailty that become more common with age but does not discriminate the components that do not, for example, unintended weight loss or exhaustion. There is no advantage in using TUG instead of gait speed with respect to identifying frailty. CONCLUSIONS: TUG is a sensitive and specific measure of frailty that offers advantages in its measurement where the full application or interpretation of Fried's criteria is impracticable; however, TUG cannot be used to reliably identify prefrail individuals. SN - 1758-535X UR - https://www.unboundmedicine.com/medline/citation/22987796/Using_timed_up_and_go_to_identify_frail_members_of_the_older_population_ L2 - https://academic.oup.com/biomedgerontology/article-lookup/doi/10.1093/gerona/gls190 DB - PRIME DP - Unbound Medicine ER -