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Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis in a young Lebanese girl.
J Child Neurol. 2013 Oct; 28(10):1222-5.JC

Abstract

Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a recently recognized autoimmune neurologic disorder that presents with severe neuropsychiatric symptoms in previously healthy children. A 4-year-old Lebanese girl presented with new-onset behavioral changes, orofacial dyskinesias, fluctuation in consciousness, inability to walk, and mutism. Antibodies directed against NMDA receptors were detected in the patient's serum and cerebrospinal fluid. Prompt treatment with a single course of intravenous immunoglobulin resulted in early complete recovery. This is the first case report of a Middle Eastern child affected with this condition.

Authors+Show Affiliations

1Division of Pediatric Neurology, Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon.No affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22992990

Citation

Safadieh, Layal, and Omar Dabbagh. "Anti-N-methyl-D-aspartate (NMDA) Receptor Encephalitis in a Young Lebanese Girl." Journal of Child Neurology, vol. 28, no. 10, 2013, pp. 1222-5.
Safadieh L, Dabbagh O. Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis in a young Lebanese girl. J Child Neurol. 2013;28(10):1222-5.
Safadieh, L., & Dabbagh, O. (2013). Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis in a young Lebanese girl. Journal of Child Neurology, 28(10), 1222-5. https://doi.org/10.1177/0883073812456085
Safadieh L, Dabbagh O. Anti-N-methyl-D-aspartate (NMDA) Receptor Encephalitis in a Young Lebanese Girl. J Child Neurol. 2013;28(10):1222-5. PubMed PMID: 22992990.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis in a young Lebanese girl. AU - Safadieh,Layal, AU - Dabbagh,Omar, Y1 - 2012/09/18/ PY - 2012/9/21/entrez PY - 2012/9/21/pubmed PY - 2014/5/8/medline KW - Middle East KW - NMDA KW - anti–N-methyl-d-aspartate receptor encephalitis KW - early recovery SP - 1222 EP - 5 JF - Journal of child neurology JO - J Child Neurol VL - 28 IS - 10 N2 - Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a recently recognized autoimmune neurologic disorder that presents with severe neuropsychiatric symptoms in previously healthy children. A 4-year-old Lebanese girl presented with new-onset behavioral changes, orofacial dyskinesias, fluctuation in consciousness, inability to walk, and mutism. Antibodies directed against NMDA receptors were detected in the patient's serum and cerebrospinal fluid. Prompt treatment with a single course of intravenous immunoglobulin resulted in early complete recovery. This is the first case report of a Middle Eastern child affected with this condition. SN - 1708-8283 UR - https://www.unboundmedicine.com/medline/citation/22992990/Anti_N_methyl_D_aspartate__NMDA__receptor_encephalitis_in_a_young_Lebanese_girl_ L2 - https://journals.sagepub.com/doi/10.1177/0883073812456085?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -