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Microbial biotransformation of kurarinone by Cunninghamella echinulata AS 3.3400.
J Asian Nat Prod Res. 2012; 14(11):1002-7.JA

Abstract

In this paper, microbial transformation of kurarinone (1) by Cunninghamella echinulata AS 3.3400 was investigated and four transformed products were isolated and identified as 6″-hydroxykurarinone (2), 4″,5″,8″-trihydroxynorkurarinone (3), norkurarinone (4), and kurarinone-7-O-β-glucoside (5), respectively. Among them, 3 and 5 are new compounds, and the rare glycosylation in microbial transformation was observed. In addition, the cytotoxicities of transformed products (2-5) were also investigated.

Authors+Show Affiliations

State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23009297

Citation

Shi, Yan-Qiu, et al. "Microbial Biotransformation of Kurarinone By Cunninghamella Echinulata as 3.3400." Journal of Asian Natural Products Research, vol. 14, no. 11, 2012, pp. 1002-7.
Shi YQ, Xin XL, Yuan QP, et al. Microbial biotransformation of kurarinone by Cunninghamella echinulata AS 3.3400. J Asian Nat Prod Res. 2012;14(11):1002-7.
Shi, Y. Q., Xin, X. L., Yuan, Q. P., Wang, C. Y., Zhang, B. J., Hou, J., Tian, Y., Deng, S., Huang, S. S., & Ma, X. C. (2012). Microbial biotransformation of kurarinone by Cunninghamella echinulata AS 3.3400. Journal of Asian Natural Products Research, 14(11), 1002-7. https://doi.org/10.1080/10286020.2012.681049
Shi YQ, et al. Microbial Biotransformation of Kurarinone By Cunninghamella Echinulata as 3.3400. J Asian Nat Prod Res. 2012;14(11):1002-7. PubMed PMID: 23009297.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Microbial biotransformation of kurarinone by Cunninghamella echinulata AS 3.3400. AU - Shi,Yan-Qiu, AU - Xin,Xiu-Lan, AU - Yuan,Qi-Peng, AU - Wang,Chang-Yuan, AU - Zhang,Bao-Jing, AU - Hou,Jie, AU - Tian,Yan, AU - Deng,Sa, AU - Huang,Shan-Shan, AU - Ma,Xiao-Chi, Y1 - 2012/09/25/ PY - 2012/9/27/entrez PY - 2012/9/27/pubmed PY - 2013/3/13/medline SP - 1002 EP - 7 JF - Journal of Asian natural products research JO - J Asian Nat Prod Res VL - 14 IS - 11 N2 - In this paper, microbial transformation of kurarinone (1) by Cunninghamella echinulata AS 3.3400 was investigated and four transformed products were isolated and identified as 6″-hydroxykurarinone (2), 4″,5″,8″-trihydroxynorkurarinone (3), norkurarinone (4), and kurarinone-7-O-β-glucoside (5), respectively. Among them, 3 and 5 are new compounds, and the rare glycosylation in microbial transformation was observed. In addition, the cytotoxicities of transformed products (2-5) were also investigated. SN - 1477-2213 UR - https://www.unboundmedicine.com/medline/citation/23009297/Microbial_biotransformation_of_kurarinone_by_Cunninghamella_echinulata_AS_3_3400_ L2 - http://www.tandfonline.com/doi/full/10.1080/10286020.2012.681049 DB - PRIME DP - Unbound Medicine ER -