Tags

Type your tag names separated by a space and hit enter

Asymmetric 1,2-reduction of enones with potassium borohydride catalyzed by chiral N,N'-dioxide-scandium(III) complexes.
Org Lett. 2012 Oct 05; 14(19):5134-7.OL

Abstract

The first catalytic enantioselective 1,2-reduction of enones with 0.45 mol equiv potassium borohydride solution catalyzed by a chiral N,N'-dioxide-Sc(III) complex catalyst was accomplished under mild reaction conditions. A number of optically active allylic alcohols were obtained in good to excellent enantioselectivities (up to 95% ee) with nearly quantitative yields.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

He P
Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China.
Liu X
No affiliation info available
Zheng H
No affiliation info available
Li W
No affiliation info available
Lin L
No affiliation info available
Feng X
No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23013322

Citation

He, Peng, et al. "Asymmetric 1,2-reduction of Enones With Potassium Borohydride Catalyzed By Chiral N,N'-dioxide-scandium(III) Complexes." Organic Letters, vol. 14, no. 19, 2012, pp. 5134-7.
He P, Liu X, Zheng H, et al. Asymmetric 1,2-reduction of enones with potassium borohydride catalyzed by chiral N,N'-dioxide-scandium(III) complexes. Org Lett. 2012;14(19):5134-7.
He, P., Liu, X., Zheng, H., Li, W., Lin, L., & Feng, X. (2012). Asymmetric 1,2-reduction of enones with potassium borohydride catalyzed by chiral N,N'-dioxide-scandium(III) complexes. Organic Letters, 14(19), 5134-7. https://doi.org/10.1021/ol302430h
He P, et al. Asymmetric 1,2-reduction of Enones With Potassium Borohydride Catalyzed By Chiral N,N'-dioxide-scandium(III) Complexes. Org Lett. 2012 Oct 5;14(19):5134-7. PubMed PMID: 23013322.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Asymmetric 1,2-reduction of enones with potassium borohydride catalyzed by chiral N,N'-dioxide-scandium(III) complexes. AU - He,Peng, AU - Liu,Xiaohua, AU - Zheng,Haifeng, AU - Li,Wei, AU - Lin,Lili, AU - Feng,Xiaoming, Y1 - 2012/09/26/ PY - 2012/9/28/entrez PY - 2012/9/28/pubmed PY - 2012/9/28/medline SP - 5134 EP - 7 JF - Organic letters JO - Org Lett VL - 14 IS - 19 N2 - The first catalytic enantioselective 1,2-reduction of enones with 0.45 mol equiv potassium borohydride solution catalyzed by a chiral N,N'-dioxide-Sc(III) complex catalyst was accomplished under mild reaction conditions. A number of optically active allylic alcohols were obtained in good to excellent enantioselectivities (up to 95% ee) with nearly quantitative yields. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/23013322/Asymmetric_12_reduction_of_enones_with_potassium_borohydride_catalyzed_by_chiral_NN'_dioxide_scandium_III__complexes_ L2 - https://doi.org/10.1021/ol302430h DB - PRIME DP - Unbound Medicine ER -