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Characteristics and in-hospital outcomes of patients with acute coronary syndromes and heart failure in the United Arab Emirates.
BMC Res Notes. 2012 Sep 26; 5:534.BR

Abstract

BACKGROUND

Heart failure (HF) is a serious complication of acute coronary syndromes (ACS), and is associated with high in-hospital mortality and poor long-term survival. The aims of this study were to describe the clinical characteristics, management and in-hospital outcomes of coronary syndrome (ACS) patients with HF in the United Arab Emirates.

FINDINGS

The study was selected from the Gulf Registry of Acute Coronary Events (Gulf RACE), a prospective multi-national, multicenter registry of patients hospitalized with ACS in six Middle East countries. The present analysis was focused on participants admitted to various hospitals in the UAE with a diagnosis of ACS in 2007 and were analyzed in terms of HF (Killip class II/III and IV) on admission. Of 1691 patients (mean age: 52.6 ± 11.7 years; 210 Females, 1481 Males) with ACS, 356 (21%) had an admission diagnosis of HF (Killip class II/III and IV). HF patients were less frequently males (19.2% vs. 34.3%; P < 0.001). HF was more frequently associated with hypertension (64.3% vs. 43.9%; P < 0.001), hyperlipidemia (49.4% vs. 31.8%; P < 0.001) and diabetes mellitus (DM) (51.1% vs. 36.2%; P < 0.001). HF was significantly associated with in-hospital mortality (OR = 11.821; 95% CI: 5.385-25.948; P < 0.001). In multivariate logistic regression, age, hyperlipidemia, heart rate and DM were associated with higher in-hospital HF.

CONCLUSIONS

HF is observed in about 1 in 5 patients with ACS in the UAE and is associated with a significant increase in in-hospital mortality and other adverse outcomes.

Authors+Show Affiliations

Department of Internal Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates. a.shehab@uaeu.ac.aeNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23014157

Citation

Shehab, Abdulla, et al. "Characteristics and In-hospital Outcomes of Patients With Acute Coronary Syndromes and Heart Failure in the United Arab Emirates." BMC Research Notes, vol. 5, 2012, p. 534.
Shehab A, Al-Dabbagh B, Almahmeed W, et al. Characteristics and in-hospital outcomes of patients with acute coronary syndromes and heart failure in the United Arab Emirates. BMC Res Notes. 2012;5:534.
Shehab, A., Al-Dabbagh, B., Almahmeed, W., Bustani, N., Nagelkerke, N., Yusufali, A., Wassef, A., Ibrahim, M., & Brek, A. B. (2012). Characteristics and in-hospital outcomes of patients with acute coronary syndromes and heart failure in the United Arab Emirates. BMC Research Notes, 5, 534. https://doi.org/10.1186/1756-0500-5-534
Shehab A, et al. Characteristics and In-hospital Outcomes of Patients With Acute Coronary Syndromes and Heart Failure in the United Arab Emirates. BMC Res Notes. 2012 Sep 26;5:534. PubMed PMID: 23014157.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Characteristics and in-hospital outcomes of patients with acute coronary syndromes and heart failure in the United Arab Emirates. AU - Shehab,Abdulla, AU - Al-Dabbagh,Bayan, AU - Almahmeed,Wael, AU - Bustani,Nazar, AU - Nagelkerke,Nicolaas, AU - Yusufali,Afzal, AU - Wassef,Adel, AU - Ibrahim,Mohamed, AU - Brek,Azan Bin, Y1 - 2012/09/26/ PY - 2012/04/16/received PY - 2012/09/19/accepted PY - 2012/9/28/entrez PY - 2012/9/28/pubmed PY - 2013/6/1/medline SP - 534 EP - 534 JF - BMC research notes JO - BMC Res Notes VL - 5 N2 - BACKGROUND: Heart failure (HF) is a serious complication of acute coronary syndromes (ACS), and is associated with high in-hospital mortality and poor long-term survival. The aims of this study were to describe the clinical characteristics, management and in-hospital outcomes of coronary syndrome (ACS) patients with HF in the United Arab Emirates. FINDINGS: The study was selected from the Gulf Registry of Acute Coronary Events (Gulf RACE), a prospective multi-national, multicenter registry of patients hospitalized with ACS in six Middle East countries. The present analysis was focused on participants admitted to various hospitals in the UAE with a diagnosis of ACS in 2007 and were analyzed in terms of HF (Killip class II/III and IV) on admission. Of 1691 patients (mean age: 52.6 ± 11.7 years; 210 Females, 1481 Males) with ACS, 356 (21%) had an admission diagnosis of HF (Killip class II/III and IV). HF patients were less frequently males (19.2% vs. 34.3%; P < 0.001). HF was more frequently associated with hypertension (64.3% vs. 43.9%; P < 0.001), hyperlipidemia (49.4% vs. 31.8%; P < 0.001) and diabetes mellitus (DM) (51.1% vs. 36.2%; P < 0.001). HF was significantly associated with in-hospital mortality (OR = 11.821; 95% CI: 5.385-25.948; P < 0.001). In multivariate logistic regression, age, hyperlipidemia, heart rate and DM were associated with higher in-hospital HF. CONCLUSIONS: HF is observed in about 1 in 5 patients with ACS in the UAE and is associated with a significant increase in in-hospital mortality and other adverse outcomes. SN - 1756-0500 UR - https://www.unboundmedicine.com/medline/citation/23014157/Characteristics_and_in_hospital_outcomes_of_patients_with_acute_coronary_syndromes_and_heart_failure_in_the_United_Arab_Emirates_ L2 - https://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-5-534 DB - PRIME DP - Unbound Medicine ER -