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Urinary stone risk and cola consumption.
Urology. 2012 Nov; 80(5):990-4.U

Abstract

OBJECTIVE

To evaluate the effect of cola consumption on urinary stone risk factors in a controlled metabolic environment with a prospective cross-over study.

METHODS

Thirteen participants (10 normal and 3 calcium oxalate stone-formers) underwent 2 6-day phases on a controlled metabolic diet. During phase 1, subjects ingested 1 liter of cola daily, followed by a 3-week washout period. During phase 2, subjects ingested 1 liter of deionized water daily. Twenty-four-hour urine collections and serum metabolic panels were obtained for stone risk factors at the end of each phase. Urine and serum results of the cola phase were compared with those of the water phase.

RESULT

Normal subjects and stone-formers were combined for analysis after determining no significant difference between the 2 groups. No significant differences were found among cola and water treatment groups for normal subjects, stone-formers, or the pooled group.

CONCLUSION

Cola exerts no detectable change in urinary risk factors associated with calcium oxalate stone formation. Cola consumption may not increase stone risk and may be an acceptable alternative source of daily fluid for patients unwilling to increase water consumption.

Authors+Show Affiliations

Department of Urology and General Clinical Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

23017784

Citation

Herrel, Lindsey, et al. "Urinary Stone Risk and Cola Consumption." Urology, vol. 80, no. 5, 2012, pp. 990-4.
Herrel L, Pattaras J, Solomon T, et al. Urinary stone risk and cola consumption. Urology. 2012;80(5):990-4.
Herrel, L., Pattaras, J., Solomon, T., & Ogan, K. (2012). Urinary stone risk and cola consumption. Urology, 80(5), 990-4. https://doi.org/10.1016/j.urology.2012.07.003
Herrel L, et al. Urinary Stone Risk and Cola Consumption. Urology. 2012;80(5):990-4. PubMed PMID: 23017784.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Urinary stone risk and cola consumption. AU - Herrel,Lindsey, AU - Pattaras,John, AU - Solomon,Tania, AU - Ogan,Kenneth, Y1 - 2012/09/25/ PY - 2012/04/11/received PY - 2012/06/22/revised PY - 2012/07/03/accepted PY - 2012/9/29/entrez PY - 2012/9/29/pubmed PY - 2013/1/9/medline SP - 990 EP - 4 JF - Urology JO - Urology VL - 80 IS - 5 N2 - OBJECTIVE: To evaluate the effect of cola consumption on urinary stone risk factors in a controlled metabolic environment with a prospective cross-over study. METHODS: Thirteen participants (10 normal and 3 calcium oxalate stone-formers) underwent 2 6-day phases on a controlled metabolic diet. During phase 1, subjects ingested 1 liter of cola daily, followed by a 3-week washout period. During phase 2, subjects ingested 1 liter of deionized water daily. Twenty-four-hour urine collections and serum metabolic panels were obtained for stone risk factors at the end of each phase. Urine and serum results of the cola phase were compared with those of the water phase. RESULT: Normal subjects and stone-formers were combined for analysis after determining no significant difference between the 2 groups. No significant differences were found among cola and water treatment groups for normal subjects, stone-formers, or the pooled group. CONCLUSION: Cola exerts no detectable change in urinary risk factors associated with calcium oxalate stone formation. Cola consumption may not increase stone risk and may be an acceptable alternative source of daily fluid for patients unwilling to increase water consumption. SN - 1527-9995 UR - https://www.unboundmedicine.com/medline/citation/23017784/Urinary_stone_risk_and_cola_consumption_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0090-4295(12)00769-8 DB - PRIME DP - Unbound Medicine ER -