Tags

Type your tag names separated by a space and hit enter

Soft drink intake in relation to incident ischemic heart disease, stroke, and stroke subtypes in Japanese men and women: the Japan Public Health Centre-based study cohort I.
Am J Clin Nutr. 2012 Dec; 96(6):1390-7.AJ

Abstract

BACKGROUND

Soft drink intake has been associated with obesity and diabetes, but its relation with risk of cardiovascular disease (CVD) is limited.

OBJECTIVE

We examined the association between soft drink intake and risk of CVD in a Japanese population.

DESIGN

This was a prospective study in 39,786 Japanese men and women aged 40-59 y in which soft drink intake was determined by using a self-administered food-frequency questionnaire. Follow-up was from 1990 to 2008. HRs and 95% CIs of incidence were calculated according to categories of soft drink intake.

RESULTS

During 18 y of follow-up, we ascertained 453 incident cases of ischemic heart disease (IHD) and 1922 cases of stroke, including 859 hemorrhagic and 1047 ischemic strokes. Soft drink intake was positively associated with risk of total stroke and more specifically ischemic stroke for women; the multivariable HR (95% CI) in the highest soft drink intake (almost every day) category compared with the lowest intake (never or rarely) category was 1.21 (0.88, 1.68; P-trend = 0.02) for total stroke and 1.83 (1.22, 2.75; P-trend = 0.001) for ischemic stroke. That association did not change significantly after the exclusion of early incident cases within 3-9 y from baseline. A nonsignificant inverse trend for risks of total and ischemic strokes was shown for men, and it was weakened after the exclusion of early incident cases or after the exclusion of participants with baseline comorbidities. Soft drink intake was not associated with risk of IHD or hemorrhagic stroke for either sex.

CONCLUSION

Soft drink intake is associated with higher risk of ischemic stroke for women.

Authors+Show Affiliations

Public Health Medicine, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Suita Shi, Osaka, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23076619

Citation

Eshak, Ehab S., et al. "Soft Drink Intake in Relation to Incident Ischemic Heart Disease, Stroke, and Stroke Subtypes in Japanese Men and Women: the Japan Public Health Centre-based Study Cohort I." The American Journal of Clinical Nutrition, vol. 96, no. 6, 2012, pp. 1390-7.
Eshak ES, Iso H, Kokubo Y, et al. Soft drink intake in relation to incident ischemic heart disease, stroke, and stroke subtypes in Japanese men and women: the Japan Public Health Centre-based study cohort I. Am J Clin Nutr. 2012;96(6):1390-7.
Eshak, E. S., Iso, H., Kokubo, Y., Saito, I., Yamagishi, K., Inoue, M., & Tsugane, S. (2012). Soft drink intake in relation to incident ischemic heart disease, stroke, and stroke subtypes in Japanese men and women: the Japan Public Health Centre-based study cohort I. The American Journal of Clinical Nutrition, 96(6), 1390-7. https://doi.org/10.3945/ajcn.112.037903
Eshak ES, et al. Soft Drink Intake in Relation to Incident Ischemic Heart Disease, Stroke, and Stroke Subtypes in Japanese Men and Women: the Japan Public Health Centre-based Study Cohort I. Am J Clin Nutr. 2012;96(6):1390-7. PubMed PMID: 23076619.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Soft drink intake in relation to incident ischemic heart disease, stroke, and stroke subtypes in Japanese men and women: the Japan Public Health Centre-based study cohort I. AU - Eshak,Ehab S, AU - Iso,Hiroyasu, AU - Kokubo,Yoshihiro, AU - Saito,Isao, AU - Yamagishi,Kazumasa, AU - Inoue,Manami, AU - Tsugane,Shoichiro, Y1 - 2012/10/17/ PY - 2012/10/19/entrez PY - 2012/10/19/pubmed PY - 2013/1/26/medline SP - 1390 EP - 7 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 96 IS - 6 N2 - BACKGROUND: Soft drink intake has been associated with obesity and diabetes, but its relation with risk of cardiovascular disease (CVD) is limited. OBJECTIVE: We examined the association between soft drink intake and risk of CVD in a Japanese population. DESIGN: This was a prospective study in 39,786 Japanese men and women aged 40-59 y in which soft drink intake was determined by using a self-administered food-frequency questionnaire. Follow-up was from 1990 to 2008. HRs and 95% CIs of incidence were calculated according to categories of soft drink intake. RESULTS: During 18 y of follow-up, we ascertained 453 incident cases of ischemic heart disease (IHD) and 1922 cases of stroke, including 859 hemorrhagic and 1047 ischemic strokes. Soft drink intake was positively associated with risk of total stroke and more specifically ischemic stroke for women; the multivariable HR (95% CI) in the highest soft drink intake (almost every day) category compared with the lowest intake (never or rarely) category was 1.21 (0.88, 1.68; P-trend = 0.02) for total stroke and 1.83 (1.22, 2.75; P-trend = 0.001) for ischemic stroke. That association did not change significantly after the exclusion of early incident cases within 3-9 y from baseline. A nonsignificant inverse trend for risks of total and ischemic strokes was shown for men, and it was weakened after the exclusion of early incident cases or after the exclusion of participants with baseline comorbidities. Soft drink intake was not associated with risk of IHD or hemorrhagic stroke for either sex. CONCLUSION: Soft drink intake is associated with higher risk of ischemic stroke for women. SN - 1938-3207 UR - https://www.unboundmedicine.com/medline/citation/23076619/Soft_drink_intake_in_relation_to_incident_ischemic_heart_disease_stroke_and_stroke_subtypes_in_Japanese_men_and_women:_the_Japan_Public_Health_Centre_based_study_cohort_I_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.3945/ajcn.112.037903 DB - PRIME DP - Unbound Medicine ER -